Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD016593-04S2
Application #
3313776
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1981-09-29
Project End
1986-03-31
Budget Start
1984-09-01
Budget End
1986-03-31
Support Year
4
Fiscal Year
1986
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Type
Schools of Arts and Sciences
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Sethumadhavan, K; Bellino, F L (1991) Human placental estrogen synthetase (aromatase). Effect of environment on the kinetics of protein-protein and substrate-protein interactions and the production of 19-oxygenated androgen intermediates in the purified reconstituted cytochrome P450 enzyme sy J Steroid Biochem Mol Biol 39:381-94
Sethumadhavan, K; Bellino, F L; Thotakura, N R (1991) Estrogen synthetase (aromatase). The cytochrome P-450 component of the human placental enzyme is a glycoprotein. Mol Cell Endocrinol 78:25-32
Sethumadhavan, K; Bellino, F L (1990) Estrogen synthetase (aromatase) Affinity purification of antibody against the cytochrome P450 component. J Steroid Biochem 36:295-9
Huang, J R; Bellino, F L; Osawa, Y et al. (1989) Immunologic identification of the aromatase enzyme system in human endometrium. J Steroid Biochem 33:1043-7
Lobo, J O; Bellino, F L (1989) Estrogen synthetase (aromatase) activity in primary culture of human term placental cells: effects of cell preparation, growth medium, and serum on adenosine 3',5'-monophosphate response. J Clin Endocrinol Metab 69:868-74
Lobo, J O; Bellino, F L (1989) Oestrogen synthetase (aromatase) and hormone secretion in primary cultures of human placental trophoblast cells. Effects of cyclic AMP addition at the start of culture in attached and unattached cell populations. Placenta 10:377-85
Bellino, F L; Holben, L (1989) Placental estrogen synthetase (aromatase): evidence for phosphatase-dependent inactivation. Biochem Biophys Res Commun 162:498-504
Bellino, F L; Tseng, L; Lobo, J O (1987) Antisera against estrogen synthetase from human placental microsomes. Antibody characterization and cross-reactivity studies in other organs. Mol Cell Endocrinol 52:143-50
Bellino, F L; Lobo, J O (1987) Estrogen synthetase (aromatase) in cultured human term placental cells and neoplastic human trophoblast. Steroids 50:73-87
Bellino, F L; Hussa, R O (1985) Estrogen synthetase stimulation by hemin in human choriocarcinoma cell culture. Biochem Biophys Res Commun 127:232-8

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