Fecundability is the monthly probability of conception. It determines the waiting time to conception, thus affecting the length of birth intervals. Physiological and behavioral factors interact to determine fecundability. A model of these interactions has been developed and validated with data from U.S. women. This proposal extends the model by incorporating new theoretical and empirical developments; it also provides methods for testing model predictions against empirical data on the interval from marriage to first birth. Four existing sources of data will be used in the analyses. Two of these include a large number of menstrual cycles for which daily coital diaries and daily measures of urinary luteinizing hormone will be available. These data will be used to estimate the distribution of intercourse by cycle day, as well as by partners' ages, marital duration, and time since last intercourse. A third data set will be used to investigate heterogeneity in ovarian cycles and its effects on fecundability. The final collection of data, from a series of surveys in Taiwan, will provide observed distributions of first birth intervals to be analyzed using life-table techniques. The proposed research addresses several issues concerning contemporary reproductive patterns. The combination of delayed onset of childbearing and truncation of childbearing through surgical sterilization has led to concentration of reproduction in a narrow segment of most women's life spans. As a result, there are rising public concerns about the expected waiting time to next conception, the likelihood of pregnancy loss, and possible problems with pathological infertility. The proposed research provides a theoretical and empirical basis for evaluating these issues. More generally, this research is part of an effort to integrate biological processes into demographic models. The collaboration described in this proposal, with its unusual combination of biological and demographic skills, fosters an increasing dialogue between biologists and social scientists concerned with human fertility.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD020989-04A2
Application #
3319547
Study Section
Social Sciences and Population Study Section (SSP)
Project Start
1987-09-01
Project End
1995-05-31
Budget Start
1992-06-01
Budget End
1993-05-31
Support Year
4
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Georgetown University
Department
Type
Other Domestic Higher Education
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Wood, J W; Holman, D J; Yashin, A I et al. (1994) A multistate model of fecundability and sterility. Demography 31:403-26
Weinstein, M; Stark, M (1994) Behavioral and biological determinants of fecundability. Ann N Y Acad Sci 709:128-44
Weinstein, M; Wood, J; Greenfield, D D (1993) How does variation in fetal loss affect the distribution of waiting times to conception? Soc Biol 40:106-30
Galdikas, B M; Wood, J W (1990) Birth spacing patterns in humans and apes. Am J Phys Anthropol 83:185-91
Johnson, P L; Wood, J W; Weinstein, M (1990) Female fecundity in highland Papua New Guinea. Soc Biol 37:26-43
Wood, J W (1989) Fecundity and natural fertility in humans. Oxf Rev Reprod Biol 11:61-109
Johnson, P L; Wood, J W; Campbell, K L et al. (1987) Long ovarian cycles in women of highland New Guinea. Hum Biol 59:837-45