Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
7R01HD023273-05
Application #
3323349
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1991-04-01
Project End
1992-07-31
Budget Start
1991-04-01
Budget End
1991-07-31
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Luo, Ching-Wei; Dewey, Elizabeth M; Sudo, Satoko et al. (2005) Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. Proc Natl Acad Sci U S A 102:2820-5
Ben-Shlomo, Izhar; Hsueh, Aaron J W (2005) Three's company: two or more unrelated receptors pair with the same ligand. Mol Endocrinol 19:1097-109
Luo, Ching-Wei; Pisarska, Margareta D; Hsueh, Aaron J W (2005) Identification of a stanniocalcin paralog, stanniocalcin-2, in fish and the paracrine actions of stanniocalcin-2 in the mammalian ovary. Endocrinology 146:469-76
Sudo, Satoko; Kuwabara, Yoshimitsu; Park, Jae-Il et al. (2005) Heterodimeric fly glycoprotein hormone-alpha2 (GPA2) and glycoprotein hormone-beta5 (GPB5) activate fly leucine-rich repeat-containing G protein-coupled receptor-1 (DLGR1) and stimulation of human thyrotropin receptors by chimeric fly GPA2 and human GPB5. Endocrinology 146:3596-604
Morita, Hiroki; Mazerbourg, Sabine; Bouley, Donna M et al. (2004) Neonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distension. Mol Cell Biol 24:9736-43
Luo, Ching-Wei; Kawamura, Kazuhiro; Klein, Cynthia et al. (2004) Paracrine regulation of ovarian granulosa cell differentiation by stanniocalcin (STC) 1: mediation through specific STC1 receptors. Mol Endocrinol 18:2085-96
Mazerbourg, Sabine; Bouley, Donna M; Sudo, Satoko et al. (2004) Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality. Mol Endocrinol 18:2241-54
Hsu, Sheau Yu Teddy; Nakabayashi, Koji; Nishi, Shinya et al. (2003) Relaxin signaling in reproductive tissues. Mol Cell Endocrinol 202:165-70
Sudo, Satoko; Kumagai, Jin; Nishi, Shinya et al. (2003) H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2. J Biol Chem 278:7855-62
Nakabayashi, Koji; Matsumi, Hirotaka; Bhalla, Alka et al. (2002) Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor. J Clin Invest 109:1445-52

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