Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD024442-09
Application #
2199164
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1988-08-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Wayne State University
Department
Genetics
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202

  Publications

Yang, M; Kurkinen, M (1998) Cloning and developmental regulation of tissue inhibitor of metalloproteinases-3 (TIMP3) in Xenopus laevis early embryos. Gene 211:95-100
Yang, M; Kurkinen, M (1998) Cloning and characterization of a novel matrix metalloproteinase (MMP), CMMP, from chicken embryo fibroblasts. CMMP, Xenopus XMMP, and human MMP19 have a conserved unique cysteine in the catalytic domain. J Biol Chem 273:17893-900
Yang, M; Murray, M T; Kurkinen, M (1997) A novel matrix metalloproteinase gene (XMMP) encoding vitronectin-like motifs is transiently expressed in Xenopus laevis early embryo development. J Biol Chem 272:13527-33
Benbow, U; Buttice, G; Nagase, H et al. (1996) Characterization of the 46-kDa intermediates of matrix metalloproteinase 3 (stromelysin 1) obtained by site-directed mutation of phenylalanine 83. J Biol Chem 271:10715-22
Gervasi, D C; Raz, A; Dehem, M et al. (1996) Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblasts and fibrosarcoma cells. Biochem Biophys Res Commun 228:530-8
Yang, M; Hayashi, K; Hayashi, M et al. (1996) Cloning and developmental expression of a membrane-type matrix metalloproteinase from chicken. J Biol Chem 271:25548-54
Yang, M; Kurkinen, M (1994) Different mechanisms of regulation of the human stromelysin and collagenase genes. Analysis by a reverse-transcription-coupled-PCR assay. Eur J Biochem 222:651-8
Buttice, G; Kurkinen, M (1994) Oncogenes control stromelysin and collagenase gene expression. Contrib Nephrol 107:101-7
Quinones, S; Buttice, G; Kurkinen, M (1994) Promoter elements in the transcriptional activation of the human stromelysin-1 gene by the inflammatory cytokine, interleukin 1. Biochem J 302 ( Pt 2):471-7
Buttice, G; Kurkinen, M (1993) A polyomavirus enhancer A-binding protein-3 site and Ets-2 protein have a major role in the 12-O-tetradecanoylphorbol-13-acetate response of the human stromelysin gene. J Biol Chem 268:7196-204

Showing the most recent 10 out of 11 publications