Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
1R01HD025291-01
Application #
3326392
Study Section
Reproductive Biology Study Section (REB)
Project Start
1988-12-01
Project End
1993-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Marquette University
Department
Type
Schools of Arts and Sciences
DUNS #
046929621
City
Milwaukee
State
WI
Country
United States
Zip Code
53201
Downs, Stephen M; Hudson, Emma R; Hardie, D Grahame (2002) A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes. Dev Biol 245:200-12
Colton, Shannondoah A; Pieper, Galen M; Downs, Stephen M (2002) Altered meiotic regulation in oocytes from diabetic mice. Biol Reprod 67:220-31
Downs, S M; Ruan, B; Schroepfer Jr, G J (2001) Meiosis-activating sterol and the maturation of isolated mouse oocytes. Biol Reprod 64:80-9
Downs, S M (2001) A gap-junction-mediated signal, rather than an external paracrine factor, predominates during meiotic induction in isolated mouse oocytes. Zygote 9:71-82
Downs, S M (2000) Adenosine blocks hormone-induced meiotic maturation by suppressing purine de novo synthesis. Mol Reprod Dev 56:172-9
Downs, S M; Utecht, A M (1999) Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes. Biol Reprod 60:1446-52
Downs, S M (1999) Uptake and metabolism of adenosine mediate a meiosis-arresting action on mouse oocytes. Mol Reprod Dev 53:208-21
Downs, S M; Humpherson, P G; Leese, H J (1998) Meiotic induction in cumulus cell-enclosed mouse oocytes: involvement of the pentose phosphate pathway. Biol Reprod 58:1084-94
Downs, S M (1997) Hypoxanthine regulation of oocyte maturation in the mouse: insights using hypoxanthine phosphoribosyltransferase-deficient animals. Biol Reprod 57:54-62
Downs, S M; Mastropolo, A M (1997) Culture conditions affect meiotic regulation in cumulus cell-enclosed mouse oocytes. Mol Reprod Dev 46:551-66

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