The aim of this project is to further elucidate the influence of behaviors during infancy and early childhood on the development of adiposity to the age of six years. Research evidence suggests that there are two developmental periods before puberty during which marked changes in adiposity occur, the first during infancy, and the second between three and six years of age. This suggests that an interaction may occur between early and later behaviors to determine both the development of adiposity and the risk for later obesity. In a previous study we found that vigorous feeding style, denoted by high pressure suckling during the first month of life, predicted degree of adiposity at one, two, and three years of age. In addition, evidence suggested that duration of breast feeding and time of introduction of solid food were important factors determining later adiposity. To extend these findings, 200 infants will be followed from birth to six years of age with measures of suckling style, early feeding practices, childhood eating style and food intake, and childhood activity levels. Measures of genetic and socioeconomic influences will also be obtained. Outcome variables including Body Mass Index and skinfold measures will be obtained at regular intervals. Relative distribution of body fat (abdominal/hip ratio) will also be obtained since this factor has been shown to be related to cardiovascular risk factors in both older children and adults. Clarification of the interaction between early and later behaviors affecting the development of adiposity should lead to a better understanding of the way in which the environment and behavior influence the progression of adiposity and the development of obesity. Elucidation of behavioral risk factors for the development of excess adiposity, and delineation of the timing of these influences, may also enhance our ability to develop effective programs to prevent the development of obesity.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD025492-07
Application #
2199607
Study Section
Behavioral Medicine Study Section (BEM)
Project Start
1989-09-01
Project End
1998-05-31
Budget Start
1995-06-01
Budget End
1996-05-31
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Stanford University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Van Tine, Meredith L; McNicholas, Fiona; Safer, Debra L et al. (2017) Follow-up of selective eaters from childhood to adulthood. Eat Behav 26:61-65
Toyama, Hannah; Agras, W Stewart (2016) A test to identify persistent picky eaters. Eat Behav 23:66-69
Mascola, Anthony J; Bryson, Susan W; Agras, W Stewart (2010) Picky eating during childhood: a longitudinal study to age 11 years. Eat Behav 11:253-7
Deardorff, Julianna; Hayward, Chris; Wilson, Kimberly A et al. (2007) Puberty and gender interact to predict social anxiety symptoms in early adolescence. J Adolesc Health 41:102-4
Agras, W Stewart; Bryson, Susan; Hammer, Lawrence D et al. (2007) Childhood risk factors for thin body preoccupation and social pressure to be thin. J Am Acad Child Adolesc Psychiatry 46:171-8
Agras, W Stewart; Hammer, Lawrence D; McNicholas, Fiona et al. (2004) Risk factors for childhood overweight: a prospective study from birth to 9.5 years. J Pediatr 145:20-5
Jacobi, Corinna; Agras, W Stewart; Bryson, Susan et al. (2003) Behavioral validation, precursors, and concomitants of picky eating in childhood. J Am Acad Child Adolesc Psychiatry 42:76-84
Jacobi, C; Agras, W S; Hammer, L (2001) Predicting children's reported eating disturbances at 8 years of age. J Am Acad Child Adolesc Psychiatry 40:364-72
Stice, E; Agras, W S; Hammer, L D (1999) Risk factors for the emergence of childhood eating disturbances: a five-year prospective study. Int J Eat Disord 25:375-87
Agras, S; Hammer, L; McNicholas, F (1999) A prospective study of the influence of eating-disordered mothers on their children. Int J Eat Disord 25:253-62

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