Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD029495-04A1
Application #
2201930
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1992-08-01
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Sadler, T W; Merrill, Alfred H; Stevens, Victoria L et al. (2002) Prevention of fumonisin B1-induced neural tube defects by folic acid. Teratology 66:169-76
Burgoon, Jennifer M; Selhub, Jacob; Nadeau, Marie et al. (2002) Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model. Teratology 65:219-27
Fisher, M C; Zeisel, S H; Mar, M H et al. (2001) Inhibitors of choline uptake and metabolism cause developmental abnormalities in neurulating mouse embryos. Teratology 64:114-22
Sadler, T W (2000) Susceptible periods during embryogenesis of the heart and endocrine glands. Environ Health Perspect 108 Suppl 3:555-61
Foerst-Potts, L; Sadler, T W (1997) Disruption of Msx-1 and Msx-2 reveals roles for these genes in craniofacial, eye, and axial development. Dev Dyn 209:70-84
Sadler, T W (1997) Mouse embryos in culture: models for understanding diabetes-induced embryopathies and gene function. Int J Dev Biol 41:291-7
Augustine, K A; Liu, E T; Sadler, T W (1995) Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development. Teratology 51:300-10
Augustine, K A; Liu, E T; Sadler, T W (1995) Interactions of Wnt-1 and Wnt-3a are essential for neural tube patterning. Teratology 51:107-19
Sadler, T W; Liu, E T; Augustine, K A (1995) Antisense targeting of engrailed-1 causes abnormal axis formation in mouse embryos. Teratology 51:292-9
Augustine, K; Liu, E T; Sadler, T W (1993) Antisense attenuation of Wnt-1 and Wnt-3a expression in whole embryo culture reveals roles for these genes in craniofacial, spinal cord, and cardiac morphogenesis. Dev Genet 14:500-20