Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD029952-03
Application #
2202315
Study Section
Special Emphasis Panel (SRC (05))
Project Start
1993-01-01
Project End
1996-12-31
Budget Start
1995-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Texas Agrilife Research
Department
Biochemistry
Type
Schools of Earth Sciences/Natur
DUNS #
110521739
City
College Station
State
TX
Country
United States
Zip Code
77843
Harris, E D (2000) Cellular copper transport and metabolism. Annu Rev Nutr 20:291-310
Qian, Y; Mikeska, G; Harris, E D et al. (1999) Effect of lead exposure and accumulation on copper homeostasis in cultured C6 rat glioma cells. Toxicol Appl Pharmacol 158:41-9
Qian, Y; Tiffany-Castiglioni, E; Harris, E D (1998) Sequence of a Menkes-type Cu-transporting ATPase from rat C6 glioma cells: comparison of the rat protein with other mammalian Cu-transporting ATPases. Mol Cell Biochem 181:49-61
Harris, E D; Qian, Y; Tiffany-Castiglioni, E et al. (1998) Functional analysis of copper homeostasis in cell culture models: a new perspective on internal copper transport. Am J Clin Nutr 67:988S-995S
Harris, E D; Qian, Y; Reddy, M C (1998) Genes regulating copper metabolism. Mol Cell Biochem 188:57-62
Reddy, M C; Harris, E D (1998) Multiple transcripts coding for the menkes gene: evidence for alternative splicing of Menkes mRNA. Biochem J 334 ( Pt 1):71-7
Qian, Y; Tiffany-Castiglioni, E; Harris, E D (1997) A Menkes P-type ATPase involved in copper homeostasis in the central nervous system of the rat. Brain Res Mol Brain Res 48:60-6
Qian, Y; Majumdar, S; Reddy, M C et al. (1996) Coincident expression of Menkes gene with copper efflux in human placental cells. Am J Physiol 270:C1880-4
Qian, Y; Tiffany-Castiglioni, E; Harris, E D (1996) Functional analysis of a genetic defect of copper transport (Menkes disease) in different cell lines. Am J Physiol 271:C378-84
Qian, Y; Tiffany-Castiglioni, E; Harris, E D (1995) Copper transport and kinetics in cultured C6 rat glioma cells. Am J Physiol 269:C892-8

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