Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD041577-02
Application #
6699983
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Program Officer
Ilekis, John V
Project Start
2003-02-01
Project End
2008-01-31
Budget Start
2004-02-01
Budget End
2005-01-31
Support Year
2
Fiscal Year
2004
Total Cost
$262,800
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Roland, Cynthia S; Hu, Jian; Ren, Chun-E et al. (2016) Morphological changes of placental syncytium and their implications for the pathogenesis of preeclampsia. Cell Mol Life Sci 73:365-76
Ren, Chun-E; Zhu, Xueqiong; Li, Jinping et al. (2015) Microarray analysis on gene regulation by estrogen, progesterone and tamoxifen in human endometrial stromal cells. Int J Mol Sci 16:5864-85
Chu, Yongli; Wang, Yanlin; Zhang, Guanghua et al. (2014) Chromatin composition alterations and the critical role of MeCP2 for epigenetic silencing of progesterone receptor-B gene in endometrial cancers. Cell Mol Life Sci 71:3393-408
Gonzalez-Bosquet, Jesus; Chu, Yongli; Chen, Hai Bin et al. (2014) Development of an intracellular, DNA methyltransferase-specific, and gene-specific assay for studying dynamic DNA methylation. Curr Pharm Des 20:1664-73
Huang, Qiang; Chen, Haibin; Li, Jinping et al. (2014) Epigenetic and non-epigenetic regulation of syncytin-1 expression in human placenta and cancer tissues. Cell Signal 26:648-56
He, Zhi-ming; Li, Jinping; Hwa, Yi Lisa et al. (2014) Transition of LINE-1 DNA methylation status and altered expression in first and third trimester placentas. PLoS One 9:e96994
Huang, Qiang; Chen, Haibin; Wang, Fengchao et al. (2014) Reduced syncytin-1 expression in choriocarcinoma BeWo cells activates the calpain1-AIF-mediated apoptosis, implication for preeclampsia. Cell Mol Life Sci 71:3151-64
Ma, Xiaoling; Li, Jinping; Brost, Brian et al. (2014) Decreased expression and DNA methylation levels of GATAD1 in preeclamptic placentas. Cell Signal 26:959-67
Huang, Qiang; Li, Jinping; Wang, Fengchao et al. (2013) Syncytin-1 modulates placental trophoblast cell proliferation by promoting G1/S transition. Cell Signal 25:1027-35
Singh, Brahma N; Zhou, Hongyuan; Li, Jinping et al. (2011) Preclinical studies on histone deacetylase inhibitors as therapeutic reagents for endometrial and ovarian cancers. Future Oncol 7:1415-28

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