The objective of the proposed 3-year study is to examine the interplay of genetic and environmental influences on conversational language skills and to examine how these etiologic factors relate to other cognitive and academic outcomes. To this end, the proposed research requests funds to transcribe and analyze a total of 1,450 language samples that have been or will be collected as part of the Western Reserve Reading Project (WRRP, Stephen Petrill, P.I., HD38075 &HD46167), a population-based longitudinal study of 350 same-sex twin pairs recruited from the greater Cleveland area as they enter school. In addition to the language sample data, WRRP includes assessments of reading, mathematics, general cognition, socioemotional development, and the family environment. Data will be analyzed using correlational approaches as well as confirmatory model-fitting analyses. The present study is innovative in that it provides the first large-scale twin study of language ability using measures from a conversational context. By analyzing both child and examiner utterances within the conversational exchange, this study will be one of the first to examine the possible influence of evocative gene-environment correlation. In addition, multiple measures within and across developmental domains (e.g., language, reading, math) provide the opportunity to examine the extent of etiologic overlap and specificity-an issue which remains relatively unexplored. Developing a more informed model of how genetic and environmental factors work together to yield language outcomes has important implications for developing programs and strategies that will facilitate child language ability.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD050307-03
Application #
7640811
Study Section
Language and Communication Study Section (LCOM)
Program Officer
Mccardle, Peggy D
Project Start
2007-09-13
Project End
2011-06-30
Budget Start
2009-07-01
Budget End
2011-06-30
Support Year
3
Fiscal Year
2009
Total Cost
$65,453
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Other Health Professions
Type
Other Domestic Higher Education
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Harlaar, Nicole; DeThorne, Laura Segebart; Smith, Jamie Mahurin et al. (2016) Longitudinal Effects on Early Adolescent Language: A Twin Study. J Speech Lang Hear Res 59:1059-1073
Smith, Jamie Mahurin; DeThorne, Laura; Petrill, Stephen (2015) From aardvark to ziggurat: A new tool for assessing children's use of rare vocabulary. Clin Linguist Phon 29:441-54
DeThorne, Laura Segebart; Harlaar, Nicole; Petrill, Stephen A et al. (2012) Longitudinal stability in genetic effects on children's conversational language productivity. J Speech Lang Hear Res 55:739-53
DeThorne, Laura Segebart; Deater-Deckard, Kirby; Mahurin-Smith, Jamie et al. (2011) Volubility as a mediator in the associations between conversational language measures and child temperament. Int J Lang Commun Disord 46:700-713