Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL014262-19S1
Application #
3334750
Study Section
Pathology A Study Section (PTHA)
Project Start
1990-02-01
Project End
1991-11-30
Budget Start
1990-02-01
Budget End
1990-11-30
Support Year
19
Fiscal Year
1990
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Ying, Q L; Kemme, M; Simon, S R (1994) Functions of the N-terminal domain of secretory leukoprotease inhibitor. Biochemistry 33:5445-50
Liao, G; Simon, S R (1994) Temporal down-regulation of Fc gamma RIII expression and Fc gamma receptor-mediated phagocytosis in human monocyte-derived macrophages induced by TNF-alpha and IL-1 beta. J Leukoc Biol 55:702-10
Tyagi, S C; Simon, S R; Carter, C A (1994) Effect of pH and nonphysiological salt concentrations on human immunodeficiency virus-1 protease dimerization. Biochem Cell Biol 72:175-81
Liao, G; Simone, J; Simon, S R (1994) Paracrine downregulation of Fc gamma RIII in human monocyte-derived macrophages induced by phagocytosis of nonopsonized particles. Blood 83:2294-304
Mallya, S K; Hall, J E; Lee, H M et al. (1994) Interaction of matrix metalloproteinases with serine protease inhibitors. New potential roles for matrix metalloproteinase inhibitors. Ann N Y Acad Sci 732:303-14
Tyagi, S C; Simon, S R (1994) Elastin-derived peptide binding to a hydrophobic domain on neutrophil elastase. Biochem Cell Biol 72:419-27
Rinehart, A R; Mallya, S; Simon, S R (1993) Human alpha 1-proteinase inhibitor binds to extracellular matrix in vitro. Am J Respir Cell Mol Biol 9:666-79
Ying, Q L; Simon, S R (1993) Kinetics of the inhibition of human leukocyte elastase by elafin, a 6-kilodalton elastase-specific inhibitor from human skin. Biochemistry 32:1866-74
Sorsa, T; Lindy, O; Konttinen, Y T et al. (1993) Doxycycline in the protection of serum alpha-1-antitrypsin from human neutrophil collagenase and gelatinase. Antimicrob Agents Chemother 37:592-4
Tyagi, S C; Simon, S R (1993) Regulation of neutrophil elastase activity by elastin-derived peptide. J Biol Chem 268:16513-8

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