Abstract

The objectives of this research proposal are to define better the clinical applications and underlying physiology of the relaxation response as related to hypnotic responsivity and to sympathetic nervous system activity. Attention will be focused upon (1) the relation of hypnotic responsivity of borderline hypertensive patients to their blood pressure changes associated with elicitation of the relaxation response, and the relation of these parameters to brain norepinephrine levels as indicated by urinary MHPG assay; (2) the relation between elicitation of the relaxation response and hypnotic responsivity to oxygen consumption while exercising at a fixed work intensity; (3) changes in sympathetic nervous system reactivity measured by plasma norepinpehrine levels and changes in brain norepinephrine levels as measured by urinary MHPG assays which are associated with elicitation of the relaxation response and their relation to hypnotic responsivity.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL022727-07
Application #
3337025
Study Section
Behavioral Medicine Study Section (BEM)
Project Start
1978-12-01
Project End
1985-11-30
Budget Start
1984-12-01
Budget End
1985-11-30
Support Year
7
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code

  Publications

Jacobs, G D; Rosenberg, P A; Friedman, R et al. (1993) Multifactor behavioral treatment of chronic sleep-onset insomnia using stimulus control and the relaxation response. A preliminary study. Behav Modif 17:498-509
Myers, S S; Benson, H (1992) Psychological factors in healing: a new perspective on an old debate. Behav Med 18:5-11
Caudill, M; Schnable, R; Zuttermeister, P et al. (1991) Decreased clinic use by chronic pain patients: response to behavioral medicine intervention. Clin J Pain 7:305-10
Goodale, I L; Domar, A D; Benson, H (1990) Alleviation of premenstrual syndrome symptoms with the relaxation response. Obstet Gynecol 75:649-55
Domar, A D; Seibel, M M; Benson, H (1990) The mind/body program for infertility: a new behavioral treatment approach for women with infertility. Fertil Steril 53:246-9
Benson, H; Malhotra, M S; Goldman, R F et al. (1990) Three case reports of the metabolic and electroencephalographic changes during advanced Buddhist meditation techniques. Behav Med 16:90-5
Mandle, C L; Domar, A D; Harrington, D P et al. (1990) Relaxation response in femoral angiography. Radiology 174:737-9
Hellman, C J; Budd, M; Borysenko, J et al. (1990) A study of the effectiveness of two group behavioral medicine interventions for patients with psychosomatic complaints. Behav Med 16:165-73
Domar, A D; Everett, L L; Keller, M G (1989) Preoperative anxiety: is it a predictable entity? Anesth Analg 69:763-7
Leserman, J; Stuart, E M; Mamish, M E et al. (1989) The efficacy of the relaxation response in preparing for cardiac surgery. Behav Med 15:111-7

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