Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL024230-10
Application #
3337550
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1979-08-01
Project End
1990-04-30
Budget Start
1990-01-01
Budget End
1990-04-30
Support Year
10
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Upstate Medical University
Department
Type
Schools of Medicine
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210
Rosebrough, S F (1993) Plasma stability and pharmacokinetics of radiolabeled deferoxamine-biotin derivatives. J Pharmacol Exp Ther 265:408-15
Rosebrough, S F (1993) Pharmacokinetics and biodistribution of radiolabeled avidin, streptavidin and biotin. Nucl Med Biol 20:663-8
Kudryk, B J; Bini, A; Rosebrough, S F et al. (1991) Fibrinogen-fibrin: preparation and use of monoclonal antibodies as diagnostics. Biotechnology 19:281-313
Rosebrough, S F; McAfee, J G; Grossman, Z D et al. (1990) Thrombus imaging: a comparison of radiolabeled GC4 and T2G1s fibrin-specific monoclonal antibodies. J Nucl Med 31:1048-54
McAfee, J G; Kopecky, R T; Frymoyer, P A (1990) Nuclear medicine comes of age: its present and future roles in diagnosis. Radiology 174:609-20
Rosebrough, S F; McAfee, J G; Grossman, Z D et al. (1989) Immunoreactivity of 111In and 131I fibrin-specific monoclonal antibody used for thrombus imaging. J Immunol Methods 116:123-9
Rosebrough, S F; Grossman, Z D; McAfee, J G et al. (1988) Thrombus imaging with indium-111 and iodine-131-labeled fibrin-specific monoclonal antibody and its F(ab')2 and Fab fragments. J Nucl Med 29:1212-22
Rosebrough, S F; Grossman, Z D; McAfee, J G et al. (1987) Aged venous thrombi: radioimmunoimaging with fibrin-specific monoclonal antibody. Radiology 162:575-7
Grossman, Z D; Rosebrough, S F; McAfee, J G et al. (1987) Imaging fresh venous thrombi in the dog with I-131 and In-111 labeled fibrin-specific monoclonal antibody and F(ab')2 fragments. Radiographics 7:913-21
Rosebrough, S F; Grossman, Z D; McAfee, J G (1986) Purification of fibrin-specific monoclonal antibody from ascites fluid by preparative isoelectric focusing. Immunol Lett 12:147-51

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