Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL027993-11
Application #
2216199
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1983-05-01
Project End
1996-12-31
Budget Start
1995-01-05
Budget End
1996-12-31
Support Year
11
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Temple University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Bakhshi, M R; Sinha, D; Vora, R K et al. (1996) Primary binding domain of bovine von Willebrand factor fragment expressed in E. coli. Thromb Haemost 75:196-202
Sinha, D; Bakhshi, M R; Vora, R K et al. (1996) Engineering DNA and protein chimeras utilizing coding sequences of restriction sites. Anal Biochem 238:205-8
Janel, N; Schwachtgen, J L; Bakhshi, M R et al. (1995) Comparison of the 5'-flanking sequences of the human and bovine von Willebrand factor-encoding genes reveals alternation of highly homologous domains with species-specific Alu-type repeats. Gene 167:291-5
Sinha, D; Yang, X; Emig, F et al. (1994) Isolation and characterization of two protease inhibitors from bovine plasma. J Biochem 115:387-91
Sinha, D; Bakhshi, M; Vora, R (1994) Ligand binding assays with recombinant proteins refolded on an affinity matrix. Biotechniques 17:509-12, 514
Sinha, D; Bakhshi, M; Kunapuli, S et al. (1994) ASP514 within the A1 domain of bovine von Willebrand factor is required for interaction with platelet glycoprotein Ib. Biochem Biophys Res Commun 203:881-8
Peng, M; Lu, W; Beviglia, L et al. (1993) Echicetin: a snake venom protein that inhibits binding of von Willebrand factor and alboaggregins to platelet glycoprotein Ib. Blood 81:2321-8
Bakhshi, M R; Myers, J C; Howard, P S et al. (1992) Sequencing of the primary adhesion domain of bovine von Willebrand factor. Biochim Biophys Acta 1132:325-8
Peng, M; Lu, W; Kirby, E P (1992) Characterization of three alboaggregins purified from Trimeresurus albolabris venom. Thromb Haemost 67:702-7
Peng, M; Lu, W; Kirby, E P (1991) Alboaggregin-B: a new platelet agonist that binds to platelet membrane glycoprotein Ib. Biochemistry 30:11529-36

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