Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL030926-10
Application #
2216730
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1984-09-01
Project End
1997-06-30
Budget Start
1994-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Rouslin, W; Broge, C W (1996) Isoform-independent heart rate-related variation in cardiac myofibrillar Ca(2+)-activated Mg(2+)-ATPase activity. Am J Physiol 270:C1271-6
Rouslin, W; Broge, C W (1996) Novel difference in IF1 reactivity to Zn2+ in rabbit versus rat cardiomyocytes, mitochondria, and submitochondrial particles. Biochem Biophys Res Commun 227:8-14
Rouslin, W; Broge, C W (1996) IF1 function in situ in uncoupler-challenged ischemic rabbit, rat, and pigeon hearts. J Biol Chem 271:23638-41
Rouslin, W; Frank, G D; Broge, C W (1995) Content and binding characteristics of the mitochondrial ATPase inhibitor, IF1, in the tissues of several slow and fast heart-rate homeothermic species and in two poikilotherms. J Bioenerg Biomembr 27:117-25
Rouslin, W; Broge, C W; Guerrieri, F et al. (1995) ATPase activity, IF1 content, and proton conductivity of ESMP from control and ischemic slow and fast heart-rate hearts. J Bioenerg Biomembr 27:459-66
Rouslin, W; Broge, C W (1994) Analysis of factors affecting functional assays for estimating IF1, the mitochondrial ATPase inhibitor. Anal Biochem 222:68-75
Rouslin, W; Broge, C W (1993) Mechanisms of ATP conservation during ischemia in slow and fast heart rate hearts. Am J Physiol 264:C209-16
Rouslin, W; Broge, C W (1993) Factors affecting the species-homologous and species-heterologous binding of mitochondrial ATPase inhibitor, IF1, to the mitochondrial ATPase of slow and fast heart-rate hearts. Arch Biochem Biophys 303:443-50
Rouslin, W; Broge, C W; Chernyak, B V (1993) Effects of Zn2+ on the activity and binding of the mitochondrial ATPase inhibitor protein, IF1. J Bioenerg Biomembr 25:297-306
Rouslin, W; Broge, C W; Chernyak, B V (1992) Zn2+ allows differentiation between two kinds of IF1-ATPase interaction in intact mitochondria. Ann N Y Acad Sci 671:507-8

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