Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL037702-08
Application #
2218547
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1986-09-30
Project End
1997-12-31
Budget Start
1994-08-01
Budget End
1997-12-31
Support Year
8
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Upstate Medical University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210
Zhang, C; Osinska, H E; Lemanski, S L et al. (2005) Changes in myofibrils and cytoskeleton of neonatal hamster myocardial cells in culture: an immunofluorescence study. Tissue Cell 37:435-45
Spinner, Belinda J; Zajdel, Robert W; McLean, Matthew D et al. (2002) Characterization of a TM-4 type tropomyosin that is essential for myofibrillogenesis and contractile activity in embryonic hearts of the Mexican axolotl. J Cell Biochem 85:747-61
Bhatia, R; Dube, D K; Gaur, A et al. (1999) Expression of axolotl RNA-binding protein during development of the Mexican axolotl. Cell Tissue Res 297:283-90
Gaur, A; Dube, D K; Lemanski, L F (1998) Cloning, sequencing and expression of a novel homeobox gene AxNox-1 from the Mexican axolotl. Gene 216:179-88
Gaur, A; Bhatia, R; Spring-Mills, E et al. (1998) The heart of metamorphosing Mexican axolotl but not that of the cardiac mutant is associated with the upregulation of Hox A5. Biochem Biophys Res Commun 245:746-51
Bhatia, R; Gaur, A; Lemanski, L F et al. (1998) Cloning and sequencing of the cDNA for an RNA-binding protein from the Mexican axolotl: binding affinity of the in vitro synthesized protein. Biochim Biophys Acta 1398:265-74
Zajdel, R W; McLean, M D; Lemanski, S L et al. (1998) Ectopic expression of tropomyosin promotes myofibrillogenesis in mutant axolotl hearts. Dev Dyn 213:412-20
Zajdel, R W; Zhu, Y; Fransen, M E et al. (1997) A primary cell culture model for defective cardiac myofibrillogenesis in Mexican axolotl embryos. In Vitro Cell Dev Biol Anim 33:677-80
Lemanski, S F; Kovacs, C P; Lemanski, L F (1997) Analysis of the three-dimensional distributions of alpha-actinin, ankyrin, and filamin in developing hearts of normal and cardiac mutant axolotls (Ambystoma mexicanum). Anat Embryol (Berl) 195:155-63
Luque, E A; Spinner, B J; Dube, S et al. (1997) Differential expression of a novel isoform of alpha-tropomyosin in cardiac and skeletal muscle of the Mexican axolotl (Ambystoma mexicanum). Gene 185:175-80

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