Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL038185-08
Application #
2218733
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1988-03-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Medical University of South Carolina
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425

  Publications

Nemoto, Shintaro; Hamawaki, Masayoshi; De Freitas, Gilberto et al. (2002) Differential effects of the angiotensin-converting enzyme inhibitor lisinopril versus the beta-adrenergic receptor blocker atenolol on hemodynamics and left ventricular contractile function in experimental mitral regurgitation. J Am Coll Cardiol 40:149-54
Nagatsu, M; Spinale, F G; Koide, M et al. (2000) Bradycardia and the role of beta-blockade in the amelioration of left ventricular dysfunction. Circulation 101:653-9
Tsutsui, H; Spinale, F G; Nagatsu, M et al. (1994) Effects of chronic beta-adrenergic blockade on the left ventricular and cardiocyte abnormalities of chronic canine mitral regurgitation. J Clin Invest 93:2639-48
Nagatsu, M; Zile, M R; Tsutsui, H et al. (1994) Native beta-adrenergic support for left ventricular dysfunction in experimental mitral regurgitation normalizes indexes of pump and contractile function. Circulation 89:818-26
Nagatsu, M; Ishihara, K; Zile, M R et al. (1994) The effects of complete versus incomplete mitral valve repair in experimental mitral regurgitation. J Thorac Cardiovasc Surg 107:416-23
Imamura, T; McDermott, P J; Kent, R L et al. (1994) Acute changes in myosin heavy chain synthesis rate in pressure versus volume overload. Circ Res 75:418-25
Spinale, F G; Ishihra, K; Zile, M et al. (1993) Structural basis for changes in left ventricular function and geometry because of chronic mitral regurgitation and after correction of volume overload. J Thorac Cardiovasc Surg 106:1147-57
Tsutsui, H; Urabe, Y; Mann, D L et al. (1993) Effects of chronic mitral regurgitation on diastolic function in isolated cardiocytes. Circ Res 72:1110-23
Carabello, B A; Zile, M R; Tanaka, R et al. (1992) Left ventricular hypertrophy due to volume overload versus pressure overload. Am J Physiol 263:H1137-44
Ishihara, K; Zile, M R; Kanazawa, S et al. (1992) Left ventricular mechanics and myocyte function after correction of experimental chronic mitral regurgitation by combined mitral valve replacement and preservation of the native mitral valve apparatus. Circulation 86:II16-25

Showing the most recent 10 out of 15 publications