Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL040901-04
Application #
3358237
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1990-01-01
Project End
1992-07-31
Budget Start
1991-08-01
Budget End
1992-07-31
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Saint Louis University
Department
Type
Schools of Medicine
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63103
Li, Jianjun; Hu, Weimin; Baldassare, Joseph J et al. (2003) The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci 73:1083-96
Baldassare, J J; Bi, Y; Bellone, C J (1999) The role of p38 mitogen-activated protein kinase in IL-1 beta transcription. J Immunol 162:5367-73
Cheng, J; Baldassare, J J; Raben, D M (1999) Dual coupling of the alpha-thrombin receptor to signal-transduction pathways involving phosphatidylinositol and phosphatidylcholine metabolism. Biochem J 337 ( Pt 1):97-104
Weber, J D; Cheng, J; Raben, D M et al. (1997) Ablation of Goalpha overrides G1 restriction point control through Ras/ERK/cyclin D1-CDK activities. J Biol Chem 272:17320-6
Weber, J D; Hu, W; Jefcoat Jr, S C et al. (1997) Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27. J Biol Chem 272:32966-71
Baldassare, J J; Jarpe, M B; Alferes, L et al. (1997) Nuclear translocation of RhoA mediates the mitogen-induced activation of phospholipase D involved in nuclear envelope signal transduction. J Biol Chem 272:4911-4
Cheng, J; Weber, J D; Baldassare, J J et al. (1997) Ablation of Go alpha-subunit results in a transformed phenotype and constitutively active phosphatidylcholine-specific phospholipase C. J Biol Chem 272:17312-9
Poulos, J E; Weber, J D; Bellezzo, J M et al. (1997) Fibronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells. Am J Physiol 273:G804-11
Padfield, P J; Panesar, N; Henderson, P et al. (1996) Differential effects of G-protein activators on 5-hydroxytryptamine and platelet-derived growth factor release from streptolysin-O-permeabilized human platelets. Biochem J 314 ( Pt 1):123-8
Reynolds, N J; Baldassare, J J; Henderson, P A et al. (1994) Translocation and downregulation of protein kinase C isoenzymes-alpha and -epsilon by phorbol ester and bryostatin-1 in human keratinocytes and fibroblasts. J Invest Dermatol 103:364-9

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