Molecular Mechanisms of Vldl Assembly

Davis, Roger A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL041624-04
• Application #: 3359447
• Study Section: Nutrition Study Section (NTN)
• Project Start: 1988-12-01
• Project End: 1992-06-30
• Budget Start: 1991-12-01
• Budget End: 1992-06-30
• Support Year: 4
• Fiscal Year: 1992

Institution

• Name: University of Colorado Denver
• Type: Schools of Medicine
• DUNS #: 065391526
• City: Aurora
• State: CO
• Country: United States
• Zip Code: 80045

Publications

Davis, R A (1993) The endoplasmic reticulum is the site of lipoprotein assembly and regulation of secretion. Subcell Biochem 21:169-87

Thrift, R N; Drisko, J; Dueland, S et al. (1992) Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in a nonhepatic cell line. Proc Natl Acad Sci U S A 89:9161-5

Leighton, J K; Joyner, J; Zamarripa, J et al. (1990) Fasting decreases apolipoprotein B mRNA editing and the secretion of small molecular weight apoB by rat hepatocytes: evidence that the total amount of apoB secreted is regulated post-transcriptionally. J Lipid Res 31:1663-8

Davis, R A; Thrift, R N; Wu, C C et al. (1990) Apolipoprotein B is both integrated into and translocated across the endoplasmic reticulum membrane. Evidence for two functionally distinct pools. J Biol Chem 265:10005-11

Lang, C A; Davis, R A (1990) Fish oil fatty acids impair VLDL assembly and/or secretion by cultured rat hepatocytes. J Lipid Res 31:2079-86

Davis, R A; Prewett, A B; Chan, D C et al. (1989) Intrahepatic assembly of very low density lipoproteins: immunologic characterization of apolipoprotein B in lipoproteins and hepatic membrane fractions and its intracellular distribution. J Lipid Res 30:1185-96