Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL041926-08
Application #
2220209
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1989-07-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Physiology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Trask, B C; Broekelmann, T; Ritty, T M et al. (2001) Posttranslational modifications of microfibril associated glycoprotein-1 (MAGP-1). Biochemistry 40:4372-80
Ritty, T M; Broekelmann, T; Tisdale, C et al. (1999) Processing of the fibrillin-1 carboxyl-terminal domain. J Biol Chem 274:8933-40
Park, P W; Broekelmann, T J; Mecham, B R et al. (1999) Characterization of the elastin binding domain in the cell-surface 25-kDa elastin-binding protein of staphylococcus aureus (EbpS). J Biol Chem 274:2845-50
Trask, T M; Ritty, T M; Broekelmann, T et al. (1999) N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly. Biochem J 340 ( Pt 3):693-701
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Davis, E C; Broekelmann, T J; Ozawa, Y et al. (1998) Identification of tropoelastin as a ligand for the 65-kD FK506-binding protein, FKBP65, in the secretory pathway. J Cell Biol 140:295-303
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Park, P W; Rosenbloom, J; Abrams, W R et al. (1996) Molecular cloning and expression of the gene for elastin-binding protein (ebpS) in Staphylococcus aureus. J Biol Chem 271:15803-9
Davis, E C; Mecham, R P (1996) Selective degradation of accumulated secretory proteins in the endoplasmic reticulum. A possible clearance pathway for abnormal tropoelastin. J Biol Chem 271:3787-94
Park, P W; Biedermann, K; Mecham, L et al. (1996) Lysozyme binds to elastin and protects elastin from elastase-mediated degradation. J Invest Dermatol 106:1075-80

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