Cell Stretch and Cardiac Hypertrophy

Watson, Peter A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL042365-02
• Application #: 3360534
• Study Section: Cardiovascular and Pulmonary Research A Study Section (CVA)
• Project Start: 1990-01-01
• Project End: 1992-12-31
• Budget Start: 1991-01-01
• Budget End: 1991-12-31
• Support Year: 2
• Fiscal Year: 1991

Institution

• Name: Weis Center for Research-Geisinger Clinc
• DUNS #: 079161360
• City: Danville
• State: PA
• Country: United States
• Zip Code: 17822

Publications

Johnson, R A; Desaubry, L; Bianchi, G et al. (1997) Isozyme-dependent sensitivity of adenylyl cyclases to P-site-mediated inhibition by adenine nucleosides and nucleoside 3'-polyphosphates. J Biol Chem 272:8962-6

Watson, P A; Hannan, R; Carl, L L et al. (1996) Contractile activity and passive stretch regulate tubulin mRNA and protein content in cardiac myocytes. Am J Physiol 271:C684-9

Watson, P A; Hannan, R; Carl, L L et al. (1996) Desmin gene expression in cardiac myocytes is responsive to contractile activity and stretch. Am J Physiol 270:C1228-35

Watson, P A; Giger, K E; Kempinski, A M (1995) Type I and type VIII adenylyl cyclases constitute a family whose activation is coupled to cellular deformation through the action of calcium-calmodulin. Biochem Cell Biol 73:367-72

Krupinski, J; Lehman, T C; Frankenfield, C D et al. (1992) Molecular diversity in the adenylylcyclase family. Evidence for eight forms of the enzyme and cloning of type VI. J Biol Chem 267:24858-62