Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL042833-08
Application #
2220712
Study Section
Pathology A Study Section (PTHA)
Project Start
1989-03-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Columbia University (N.Y.)
Department
Physiology
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032

  Publications

Schwarz, M A; Kandel, J; Brett, J et al. (1999) Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells. J Exp Med 190:341-54
Niitsu, Y; Hori, O; Yamaguchi, A et al. (1999) Exposure of cultured primary rat astrocytes to hypoxia results in intracellular glucose depletion and induction of glycolytic enzymes. Brain Res Mol Brain Res 74:26-34
Bohrer, H; Qiu, F; Zimmermann, T et al. (1997) Role of NFkappaB in the mortality of sepsis. J Clin Invest 100:972-85
Zhang, Y; Deng, Y; Wendt, T et al. (1996) Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor-induced tissue factor expression and fibrin deposition in mouse meth-A sarcoma. J Clin Invest 97:2213-24
Hori, O; Matsumoto, M; Kuwabara, K et al. (1996) Exposure of astrocytes to hypoxia/reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6. J Neurochem 66:973-9
Hori, O; Yan, S D; Ogawa, S et al. (1996) The receptor for advanced glycation end-products has a central role in mediating the effects of advanced glycation end-products on the development of vascular disease in diabetes mellitus. Nephrol Dial Transplant 11 Suppl 5:13-6
Marvin, M R; Libutti, S K; Kayton, M et al. (1996) A novel tumor-derived mediator that sensitizes cytokine-resistant tumors to tumor necrosis factor. J Surg Res 63:248-55
Lawson, C A; Smerling, A J; Naka, Y et al. (1995) Selective reduction of PVR by inhalation of a cGMP analogue in a porcine model of pulmonary hypertension. Am J Physiol 268:H2056-62
Yellin, M J; Brett, J; Baum, D et al. (1995) Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals. J Exp Med 182:1857-64
Yuzawa, Y; Brett, J; Fukatsu, A et al. (1995) Interaction of antibody with Forssman antigen in guinea pigs. A mechanism of adaptation to antibody- and complement-mediated injury. Am J Pathol 146:1260-72

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