Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL044399-05
Application #
2221461
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1992-04-09
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1998-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Versluis, J Pieter; Heslinga, Johannes W; Sipkema, Pieter et al. (2004) Contractile reserve but not tension is reduced in monocrotaline-induced right ventricular hypertrophy. Am J Physiol Heart Circ Physiol 286:H979-84
Cornelissen, A J; Spaan, J A; Dankelman, J et al. (2001) Evidence for stretch-induced resistance increase of proximal coronary microcirculation. Am J Physiol Heart Circ Physiol 281:H2687-96
Versluis, J P; Heslinga, J W; Sipkema, P et al. (2001) Microvascular pressure measurement reveals a coronary vascular waterfall in arterioles larger than 110 microm. Am J Physiol Heart Circ Physiol 281:H1913-8
Spaan, J A; Cornelissen, A J; Chan, C et al. (2000) Dynamics of flow, resistance, and intramural vascular volume in canine coronary circulation. Am J Physiol Heart Circ Physiol 278:H383-403
Yamamoto, S; Sipkema, P; Yin, F C (1999) Effect of vasoconstriction on coronary artery resistance changes caused by stretching surrounding myocardial tissue. Heart Vessels 14:9-14
Heslinga, J W; Allaart, C P; Yin, F C et al. (1997) Effects of contraction, perfusion pressure, and length on intramyocardial pressure in rat papillary muscle. Am J Physiol 272:H2320-6
Dijkman, M A; Heslinga, J W; Allaart, C P et al. (1997) Reoxygenated effluent of Tyrode-perfused heart affects papillary muscle contraction independent of cardiac perfusion. Cardiovasc Res 33:45-53
Dijkman, M A; Heslinga, J W; Sipkema, P et al. (1997) Perfusion-induced changes in cardiac contractility and oxygen consumption are not endothelium-dependent. Cardiovasc Res 33:593-600
Sipkema, P; Yamada, H; Yin, F C (1996) Coronary artery resistance changes depend on how surrounding myocardial tissue is stretched. Am J Physiol 270:H924-34
Dijkman, M A; Heslinga, J W; Sipkema, P et al. (1996) Perfusion-induced changes in cardiac O2 consumption and contractility are based on different mechanisms. Am J Physiol 271:H984-9

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