Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL044682-05A1
Application #
2221638
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1991-08-16
Project End
2000-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Genetics
Type
Schools of Public Health
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Helgadottir, Anna; Gretarsdottir, Solveig; Thorleifsson, Gudmar et al. (2012) Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. J Am Coll Cardiol 60:722-9
Hinterseher, Irene; Erdman, Robert; Donoso, Larry A et al. (2011) Role of complement cascade in abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 31:1653-60
Lillvis, John H; Kyo, Yoshiki; Tromp, Gerard et al. (2011) Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19. BMC Med Genet 12:14
Helgadottir, Anna; Thorleifsson, Gudmar; Magnusson, Kristinn P et al. (2008) The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet 40:217-24
Peters, D G; Zhang, X-C; Benos, P V et al. (2002) Genomic analysis of immediate/early response to shear stress in human coronary artery endothelial cells. Physiol Genomics 12:25-33
Peters, D G; Kassam, A B; Feingold, E et al. (2001) Molecular anatomy of an intracranial aneurysm: coordinated expression of genes involved in wound healing and tissue remodeling. Stroke 32:1036-42
Vorp, D A; Peters, D G; Webster, M W (1999) Gene expression is altered in perfused arterial segments exposed to cyclic flexure ex vivo. Ann Biomed Eng 27:366-71
Peters, D G; Kassam, A; St Jean, P L et al. (1999) Functional polymorphism in the matrix metalloproteinase-9 promoter as a potential risk factor for intracranial aneurysm. Stroke 30:2612-6
Peters, D G; Kassam, A B; Yonas, H et al. (1999) Comprehensive transcript analysis in small quantities of mRNA by SAGE-lite. Nucleic Acids Res 27:e39
St Jean, P; Hart, B; Webster, M et al. (1996) Alpha-1-antitrypsin deficiency in aneurysmal disease. Hum Hered 46:92-7

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