Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047469-05
Application #
2223698
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1992-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1998-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Smith, R D; Owen, W G (1999) Platelet responses to compound interactions with thrombin. Biochemistry 38:8936-47
Wysokinski, W E; McBane 2nd, R D; Owen, W G (1999) Individual propensity for arterial thrombosis. Arterioscler Thromb Vasc Biol 19:883-6
Machovich, R; Komorowicz, E; Kolev, K et al. (1999) Facilitation of plasminogen activation by denatured prothrombin. Thromb Res 94:389-94
Machovich, R; Owen, W G (1997) Denatured proteins as cofactors for plasminogen activation. Arch Biochem Biophys 344:343-9
Li, D; Sreenivasan, U; Juranic, N et al. (1997) Simulated dipeptide recognition by vancomycin. J Mol Recognit 10:73-87
Silvestro, L; Gupta, K; Weiser, J N et al. (1997) The concentration-dependent membrane activity of cecropin A. Biochemistry 36:11452-60
Machovich, R; Ajtai, K; Kolev, K et al. (1997) Myosin as cofactor and substrate in fibrinolysis. FEBS Lett 407:93-6
Fay, W P; Murphy, J G; Owen, W G (1996) High concentrations of active plasminogen activator inhibitor-1 in porcine coronary artery thrombi. Arterioscler Thromb Vasc Biol 16:1277-84
O'Marcaigh, A S; Nichols, W L; Hassinger, N L et al. (1996) Genetic analysis and functional characterization of prothrombins Corpus Christi (Arg382-Cys), Dhahran (Arg271-His), and hypoprothrombinemia. Blood 88:2611-8
Bichler, J; Heit, J A; Owen, W G (1996) Detection of thrombin in human blood by ex-vivo hirudin. Thromb Res 84:289-94

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