Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047537-03
Application #
2223737
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1993-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cedars-Sinai Medical Center
Department
Type
DUNS #
075307785
City
Los Angeles
State
CA
Country
United States
Zip Code
90048
Fournier, Mario; Huang, Zhi-Shen; Li, Hongyan et al. (2003) Insulin-like growth factor I prevents corticosteroid-induced diaphragm muscle atrophy in emphysematous hamsters. Am J Physiol Regul Integr Comp Physiol 285:R34-43
Lewis, Michael I; Li, Hongyan; Huang, Zhi-Shen et al. (2003) Influence of varying degrees of malnutrition on IGF-I expression in the rat diaphragm. J Appl Physiol 95:555-62
Lewis, Michael I; Horvitz, Gail D; Clemmons, David R et al. (2002) Role of IGF-I and IGF-binding proteins within diaphragm muscle in modulating the effects of nandrolone. Am J Physiol Endocrinol Metab 282:E483-90
Fournier, M; Lewis, M I (2000) Functional, cellular, and biochemical adaptations to elastase-induced emphysema in hamster medial scalene. J Appl Physiol 88:1327-37
Fournier, M; Lewis, M I (2000) Influences of IGF-I gene disruption on the cellular profile of the diaphragm. Am J Physiol Endocrinol Metab 278:E707-15
Lewis, M I; Fournier, M; Yeh, A Y et al. (1999) Alterations in diaphragm contractility after nandrolone administration: an analysis of potential mechanisms. J Appl Physiol 86:985-92
Biring, M S; Fournier, M; Ross, D J et al. (1998) Cellular adaptations of skeletal muscles to cyclosporine. J Appl Physiol 84:1967-75
Lewis, M I; Feinberg, A T; Fournier, M (1998) IGF-I and/or growth hormone preserve diaphragm fiber size with moderate malnutrition. J Appl Physiol 85:189-97
Sullivan, K J; Fournier, M; Lewis, M I (1998) Respiratory work in elastase treated hamsters. Respir Physiol 114:133-42
Lewis, M I; LoRusso, T J; Fournier, M (1997) Effect of insulin-like growth factor I and/or growth hormone on diaphragm of malnourished adolescent rats. J Appl Physiol 82:1064-70

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