Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047669-05
Application #
2223855
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1992-07-07
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Siragy, Helmy M; Awad, Alaa; Abadir, Peter et al. (2003) The angiotensin II type 1 receptor mediates renal interstitial content of tumor necrosis factor-alpha in diabetic rats. Endocrinology 144:2229-33
Millatt, Lesley J; Whitley, Guy StJ; Li, Dechun et al. (2003) Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension. Circulation 108:1493-8
Siragy, Helmy M; El-Kersh, Mohamed A; De Gasparo, Marc et al. (2002) Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP. J Hypertens 20:1157-63
Siragy, H M; de Gasparo, M; El-Kersh, M et al. (2001) Angiotensin-converting enzyme inhibition potentiates angiotensin II type 1 receptor effects on renal bradykinin and cGMP. Hypertension 38:183-6
Millatt, L J; Siragy, H M (2000) Renal cyclic 3',5'-guanosine monophosphate and sodium excretion in Dahl salt-resistant and Dahl salt-sensitive rats: comparison of the roles of bradykinin and nitric oxide. J Hypertens 18:1491-6
Millatt, L J; Siragy, H M (2000) Age-related changes in renal cyclic nucleotides and eicosanoids in response to sodium intake. Hypertension 35:643-7
Siragy, H M; de Gasparo, M; Carey, R M (2000) Angiotensin type 2 receptor mediates valsartan-induced hypotension in conscious rats. Hypertension 35:1074-7
Siragy, H M; Bedigian, M (1999) Mechanism of action of angiotensin-receptor blocking agents. Curr Hypertens Rep 1:289-95
Siragy, H M; Senbonmatsu, T; Ichiki, T et al. (1999) Increased renal vasodilator prostanoids prevent hypertension in mice lacking the angiotensin subtype-2 receptor. J Clin Invest 104:181-8
Siragy, H M; Carey, R M (1999) Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model. Hypertension 33:1237-42

Showing the most recent 10 out of 21 publications