Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047826-03
Application #
2223914
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Palumbo, J S; Zogg, M; Talmage, K E et al. (2004) Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction. J Thromb Haemost 2:1368-79
Currier, Angela R; Sabla, Gregg; Locaputo, Stephanie et al. (2003) Plasminogen directs the pleiotropic effects of uPA in liver injury and repair. Am J Physiol Gastrointest Liver Physiol 284:G508-15
Kufrin, Dubravka; Eslin, Don E; Bdeir, Khalil et al. (2003) Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets. Blood 102:926-33
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Bannach, Felizabel Garcia; Gutierrez, Ana; Fowler, Bruce J et al. (2002) Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression. J Biol Chem 277:38579-88
Ng, V L; Sabla, G E; Melin-Aldana, H et al. (2001) Plasminogen deficiency results in poor clearance of non-fibrin matrix and persistent activation of hepatic stellate cells after an acute injury. J Hepatol 35:781-9
Pohl, J F; Melin-Aldana, H; Sabla, G et al. (2001) Plasminogen deficiency leads to impaired lobular reorganization and matrix accumulation after chronic liver injury. Am J Pathol 159:2179-86
Drew, A F; Tucker, H L; Liu, H et al. (2001) Crescentic glomerulonephritis is diminished in fibrinogen-deficient mice. Am J Physiol Renal Physiol 281:F1157-63
Degen, J L (2001) Genetic interactions between the coagulation and fibrinolytic systems. Thromb Haemost 86:130-7
Drew, A F; Liu, H; Davidson, J M et al. (2001) Wound-healing defects in mice lacking fibrinogen. Blood 97:3691-8

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