Immunologic Properties of Vascular Smooth Muscle

Hart, Michael N.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 7R01HL048658-05
• Application #: 2224733
• Study Section: Pathology B Study Section (PTHB)
• Project Start: 1992-08-01
• Project End: 1997-06-30
• Budget Start: 1995-09-01
• Budget End: 1997-06-30
• Support Year: 5
• Fiscal Year: 1995

Institution

• Name: University of Wisconsin Madison
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 161202122
• City: Madison
• State: WI
• Country: United States
• Zip Code: 53715

Publications

Baiu, Dana Carina; Sandor, Matyas; Hart, Michael (2010) CD4+ T cells sensitized by vascular smooth muscle induce vasculitis, and interferon gamma is critical for the initiation of vascular pathology. Am J Pathol 177:3215-23

Baiu, Dana Carina; Barger, Brittany; Sandor, Matyas et al. (2005) Autoantibodies to vascular smooth muscle are pathogenic for vasculitis. Am J Pathol 166:1851-60

Swanson, Brad J; Baiu, Dana C; Sandor, Matyas et al. (2003) A small population of vasculitogenic T cells expands and has skewed T cell receptor usage after culture with syngeneic smooth muscle cells. J Autoimmun 20:125-33

Karasin, A; Macvilay, S; Hart, M N et al. (1998) Murine endothelia do not express MHC class II I-Ealpha subunit and differentially regulate I-Aalpha expression along the vascular tree. Endothelium 6:83-93

Fabry, Z; Sandor, M; Gajewski, T F et al. (1993) Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes. J Immunol 151:38-47

Fabry, Z; Fitzsimmons, K M; Herlein, J A et al. (1993) Production of the cytokines interleukin 1 and 6 by murine brain microvessel endothelium and smooth muscle pericytes. J Neuroimmunol 47:23-34