Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL048816-03
Application #
2224904
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1993-12-15
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Arizona
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Mucha, David R; Myers, Carter L; Schaeffer Jr, Richard C (2003) Endothelial contraction and monolayer hyperpermeability are regulated by Src kinase. Am J Physiol Heart Circ Physiol 284:H994-H1002
Schaeffer Jr, Richard C; Gratrix, Max L; Mucha, David R et al. (2002) The rat glomerular filtration barrier does not show negative charge selectivity. Microcirculation 9:329-42
Merkle, C J; Schuler, L A; Schaeffer Jr, R C et al. (2000) Structural and functional effects of high prolactin levels on injured endothelial cells: evidence for an endothelial prolactin receptor. Endocrine 13:37-46
Carbajal, J M; Gratrix, M L; Yu, C H et al. (2000) ROCK mediates thrombin's endothelial barrier dysfunction. Am J Physiol Cell Physiol 279:C195-204
Carbajal, J M; Schaeffer Jr, R C (1999) RhoA inactivation enhances endothelial barrier function. Am J Physiol 277:C955-64
Cohen, A W; Carbajal, J M; Schaeffer Jr, R C (1999) VEGF stimulates tyrosine phosphorylation of beta-catenin and small-pore endothelial barrier dysfunction. Am J Physiol 277:H2038-49
Carbajal, J M; Schaeffer Jr, R C (1998) H2O2 and genistein differentially modulate protein tyrosine phosphorylation, endothelial morphology, and monolayer barrier function. Biochem Biophys Res Commun 249:461-6
Diwan, A H; Honkanen, R E; Schaeffer Jr, R C et al. (1997) Inhibition of serine-threonine protein phosphatases decreases barrier function of rat pulmonary microvascular endothelial cells. J Cell Physiol 171:259-70
Schaeffer Jr, R C; Bitrick Jr, M S (1995) Effects of human alpha-thrombin and 8bromo-cAMP on large and microvessel endothelial monolayer equivalent ""pore"" radii. Microvasc Res 49:364-71