Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL049275-01A3
Application #
2225410
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1996-08-10
Project End
1997-07-31
Budget Start
1996-08-10
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York Medical College
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Valhalla
State
NY
Country
United States
Zip Code
10595
Quilley, John; Qiu, Yue (2005) K(+)-induced vasodilation in the rat kidney is dependent on the endothelium and activation of K+ channels. Eur J Pharmacol 508:193-9
Chen, Y-J; Jiang, H; Quilley, J (2003) The nitric oxide- and prostaglandin-independent component of the renal vasodilator effect of thimerosal is mediated by epoxyeicosatrienoic acids. J Pharmacol Exp Ther 304:1292-8
Qiu, Y; Quilley, J (2001) Apamin/charybdotoxin-sensitive endothelial K+ channels contribute to acetylcholine-induced, NO-dependent vasorelaxation of rat aorta. Med Sci Monit 7:1129-36
McGiff, J C; Quilley, J (2001) 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure. Curr Opin Nephrol Hypertens 10:231-7
Quilley, J; McGiff, J C (2000) Is EDHF an epoxyeicosatrienoic acid? Trends Pharmacol Sci 21:121-4
Qiu, Y; Quilley, J (1999) Vascular effects of arachidonic acid in the rat perfused heart. Role of the endothelium, cyclooxygenase, cytochrome P450, and K(+) channels. J Lipid Res 40:2177-84
Fulton, D; Mcgiff, J C; Quilley, J (1998) Pharmacological evaluation of an epoxide as the putative hyperpolarizing factor mediating the nitric oxide-independent vasodilator effect of bradykinin in the rat heart. J Pharmacol Exp Ther 287:497-503
Fulton, D; Falck, J R; McGiff, J C et al. (1998) A method for the determination of 5,6-EET using the lactone as an intermediate in the formation of the diol. J Lipid Res 39:1713-21
Mieyal, P; Fulton, D; McGiff, J C et al. (1998) NO-independent vasodilation to acetylcholine in the rat isolated kidney utilizes a charybdotoxin-sensitive, intermediate-conductance Ca(++)-activated K+ channel. J Pharmacol Exp Ther 285:659-64