Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL049591-04
Application #
2225683
Study Section
Pathology A Study Section (PTHA)
Project Start
1993-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Gao, Cunji; Sun, Weiyong; Christofidou-Solomidou, Melpo et al. (2003) PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. Blood 102:169-79
O'Brien, Christopher D; Lim, Poay; Sun, Jing et al. (2003) PECAM-1-dependent neutrophil transmigration is independent of monolayer PECAM-1 signaling or localization. Blood 101:2816-25
Ji, Guangju; O'Brien, Christopher D; Feldman, Morris et al. (2002) PECAM-1 (CD31) regulates a hydrogen peroxide-activated nonselective cation channel in endothelial cells. J Cell Biol 157:173-84
Nakada, M T; Amin, K; Christofidou-Solomidou, M et al. (2000) Antibodies against the first Ig-like domain of human platelet endothelial cell adhesion molecule-1 (PECAM-1) that inhibit PECAM-1-dependent homophilic adhesion block in vivo neutrophil recruitment. J Immunol 164:452-62
Lazaar, A L; Amrani, Y; Hsu, J et al. (1998) CD40-mediated signal transduction in human airway smooth muscle. J Immunol 161:3120-7
Christofidou-Solomidou, M; Bridges, M; Murphy, G F et al. (1997) Expression and function of endothelial cell alpha v integrin receptors in wound-induced human angiogenesis in human skin/SCID mice chimeras. Am J Pathol 151:975-83
Christofidou-Solomidou, M; Nakada, M T; Williams, J et al. (1997) Neutrophil platelet endothelial cell adhesion molecule-1 participates in neutrophil recruitment at inflammatory sites and is down-regulated after leukocyte extravasation. J Immunol 158:4872-8
Christofidou-Solomidou, M; Albelda, S M; Bennett, F C et al. (1997) Experimental production and modulation of human cytotoxic dermatitis in human-murine chimeras. Am J Pathol 150:631-9
DeLisser, H M; Christofidou-Solomidou, M; Strieter, R M et al. (1997) Involvement of endothelial PECAM-1/CD31 in angiogenesis. Am J Pathol 151:671-7
Christofidou-Solomidou, M; Longley, B J; Whitaker-Menezes, D et al. (1997) Human skin/SCID mouse chimeras as an in vivo model for human cutaneous mast cell hyperplasia. J Invest Dermatol 109:102-7

Showing the most recent 10 out of 16 publications