Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL049666-04
Application #
2225756
Study Section
Pathology B Study Section (PTHB)
Project Start
1993-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Pathology
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Upmacis, Rita K; Deeb, Ruba S; Resnick, Matthew J et al. (2004) Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells. Am J Physiol Cell Physiol 286:C1271-80
Deeb, Ruba S; Resnick, Matthew J; Mittar, Dev et al. (2002) Tyrosine nitration in prostaglandin H(2) synthase. J Lipid Res 43:1718-26
Deora, A A; Hajjar, D P; Lander, H M (2000) Recruitment and activation of Raf-1 kinase by nitric oxide-activated Ras. Biochemistry 39:9901-8
Upmacis, R K; Deeb, R S; Hajjar, D P (1999) Regulation of prostaglandin H2 synthase activity by nitrogen oxides. Biochemistry 38:12505-13
Hajjar, D P; Haberland, M E (1997) Lipoprotein trafficking in vascular cells. Molecular Trojan horses and cellular saboteurs. J Biol Chem 272:22975-8
Pomerantz, K B; Lander, H M; Summers, B et al. (1997) G-protein-mediated signaling in cholesterol-enriched arterial smooth muscle cells. 1. Reduced membrane-associated G-protein content due to diminished isoprenylation of G-gamma subunits and p21ras. Biochemistry 36:9523-31
Pomerantz, K B; Lander, H M; Summers, B et al. (1997) G-protein-mediated signaling in cholesterol-enriched arterial smooth muscle cells. 2. Role of protein kinase C-delta in the regulation of eicosanoid production. Biochemistry 36:9532-9
Hsu, H Y; Nicholson, A C; Hajjar, D P (1996) Inhibition of macrophage scavenger receptor activity by tumor necrosis factor-alpha is transcriptionally and post-transcriptionally regulated. J Biol Chem 271:7767-73
Kraemer, R; Pomerantz, K B; Kesav, S et al. (1995) Cholesterol enrichment enhances expression of sterol-carrier protein-2: implications for its function in intracellular cholesterol trafficking. J Lipid Res 36:2630-8
Marcus, A J; Hajjar, D P (1993) Vascular transcellular signaling. J Lipid Res 34:2017-31

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