Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050284-02
Application #
2226425
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Abraham, E (2000) NF-kappaB activation. Crit Care Med 28:N100-4
Arndt, P G; Fantuzzi, G; Abraham, E (2000) Expression of interleukin-18 in the lung after endotoxemia or hemorrhage-induced acute lung injury. Am J Respir Cell Mol Biol 22:708-13
Abraham, E; Carmody, A; Shenkar, R et al. (2000) Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 279:L1137-45
Abraham, E; Arcaroli, J; Carmody, A et al. (2000) HMG-1 as a mediator of acute lung inflammation. J Immunol 165:2950-4
Parsey, M V; Kaneko, D; Shenkar, R et al. (1999) Neutrophil apoptosis in the lung after hemorrhage or endotoxemia: apoptosis and migration are independent of IL-1beta. Clin Immunol 91:219-25
Abraham, E; Kaneko, D J; Shenkar, R (1999) Effects of endogenous and exogenous catecholamines on LPS-induced neutrophil trafficking and activation. Am J Physiol 276:L1-8
George, C L; Fantuzzi, G; Bursten, S et al. (1999) Effects of lisofylline on hyperoxia-induced lung injury. Am J Physiol 276:L776-85
Shenkar, R; Abraham, E (1999) Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein. J Immunol 163:954-62
Parsey, M V; Tuder, R M; Abraham, E (1998) Neutrophils are major contributors to intraparenchymal lung IL-1 beta expression after hemorrhage and endotoxemia. J Immunol 160:1007-13
Shenkar, R; Abraham, E (1997) Hemorrhage induces rapid in vivo activation of CREB and NF-kappaB in murine intraparenchymal lung mononuclear cells. Am J Respir Cell Mol Biol 16:145-52

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