Regulation of Lung Endothelial Contraction/Permeability

Garcia, Joe G. N.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL050533-03
• Application #: 2226769
• Study Section: Lung Biology and Pathology Study Section (LBPA)
• Project Start: 1994-06-01
• Project End: 1999-05-31
• Budget Start: 1996-06-01
• Budget End: 1997-05-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Indiana University-Purdue University at Indianapolis
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 005436803
• City: Indianapolis
• State: IN
• Country: United States
• Zip Code: 46202

Publications

Bogatcheva, Natalia V; Wang, Peiyi; Birukova, Anna A et al. (2006) Mechanism of fluoride-induced MAP kinase activation in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 290:L1139-45

Petrache, Irina; Birukov, Konstantin; Zaiman, Ari L et al. (2003) Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. FASEB J 17:407-16

Schaphorst, Kane L; Chiang, Eddie; Jacobs, Keri N et al. (2003) Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products. Am J Physiol Lung Cell Mol Physiol 285:L258-67

Birukov, Konstantin G; Jacobson, Jeffrey R; Flores, Alejandro A et al. (2003) Magnitude-dependent regulation of pulmonary endothelial cell barrier function by cyclic stretch. Am J Physiol Lung Cell Mol Physiol 285:L785-97

Borbiev, Talaibek; Verin, Alexander D; Birukova, Anna et al. (2003) Role of CaM kinase II and ERK activation in thrombin-induced endothelial cell barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 285:L43-54

Shikata, Yasushi; Birukov, Konstantin G; Birukova, Anna A et al. (2003) Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT. FASEB J 17:2240-9

Borbiev, T; Garcia, J G; Berin, A D (2003) [Role of phosphorylation of myosin and actin-binding proteins in endothelial permeability induced by thrombin] Bioorg Khim 29:510-7

Birukov, Konstantin G; Birukova, Anna A; Dudek, Steven M et al. (2002) Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells. Am J Respir Cell Mol Biol 26:453-64

Bogatcheva, N V; Garcia, J G N; Verin, A D (2002) Molecular mechanisms of thrombin-induced endothelial cell permeability. Biochemistry (Mosc) 67:75-84

Liu, Feng; Schaphorst, Kane L; Verin, Alexander D et al. (2002) Hepatocyte growth factor enhances endothelial cell barrier function and cortical cytoskeletal rearrangement: potential role of glycogen synthase kinase-3beta. FASEB J 16:950-62