Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050881-04
Application #
2028973
Study Section
Special Emphasis Panel (ZHL1-CSR-C (S1))
Project Start
1993-09-30
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Subbiah, M T R (2002) Estrogen replacement therapy and cardioprotection: mechanisms and controversies. Braz J Med Biol Res 35:271-6
Subbiah, M T Ravi; Abplanalp, William (2002) Evidence of increased formation of products retaining strong antioxidant activity from estradiol-17beta oxidation in the presence of human plasma lipoproteins. J Lab Clin Med 139:357-63
Scheiber, M D; Liu, J H; Subbiah, M T et al. (2001) Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women. Menopause 8:384-92
Abplanalp, W; Ravi Subbiah, M T (2001) Uptake and protection against oxidative stress by estrogen esters in THP-1 human macrophage cell lines. Gynecol Obstet Invest 51:81-4
Abplanalp, W; Scheiber, M D; Moon, K et al. (2000) Evidence for the role of high density lipoproteins in mediating the antioxidant effect of estrogens. Eur J Endocrinol 142:79-83
Abplanalp, W; Rymaszewski, M; Adamski, J et al. (1999) Evidence for interference in estradiol-17beta inactivation to estrone by oxidized low-density lipoprotein and selected lipid peroxidation products. J Lab Clin Med 134:253-9
Ayres, S; Baer, J; Subbiah, M T (1998) Exercised-induced increase in lipid peroxidation parameters in amenorrheic female athletes. Fertil Steril 69:73-7
Ayres, S; Abplanalp, W; Liu, J H et al. (1998) Mechanisms involved in the protective effect of estradiol-17beta on lipid peroxidation and DNA damage. Am J Physiol 274:E1002-8
Subbiah, M T (1998) Mechanisms of cardioprotection by estrogens. Proc Soc Exp Biol Med 217:23-9
Tang, M; Abplanalp, W; Subbiah, M T (1997) Association of estrogens with human plasma lipoproteins: studies using estradiol-17beta and its hydrophobic derivative. J Lab Clin Med 129:447-52

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