Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051469-03
Application #
2228251
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1994-07-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Jacobs, Kristi Muldoon; Pennington, J Daniel; Bisht, Kheem S et al. (2008) SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression. Int J Biol Sci 4:291-9
Brown, Kyle E; Meleah Mathahs, M; Broadhurst, Kimberly A et al. (2007) Increased hepatic telomerase activity in a rat model of iron overload: a role for altered thiol redox state? Free Radic Biol Med 42:228-35
Laszlo, Andrei; Davidson, Teri; Harvey, Amanda et al. (2006) Alterations in heat-induced radiosensitization accompanied by nuclear structure alterations in Chinese hamster cells. Int J Hyperthermia 22:43-60
Morrison, Joanna P; Coleman, Mitchell C; Aunan, Elizabeth S et al. (2005) Aging reduces responsiveness to BSO- and heat stress-induced perturbations of glutathione and antioxidant enzymes. Am J Physiol Regul Integr Comp Physiol 289:R1035-41
Ridnour, Lisa A; Sim, Julia E; Choi, Jinah et al. (2005) Nitric oxide-induced resistance to hydrogen peroxide stress is a glutamate cysteine ligase activity-dependent process. Free Radic Biol Med 38:1361-71
Ahmad, Iman M; Aykin-Burns, Nukhet; Sim, Julia E et al. (2005) Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells. J Biol Chem 280:4254-63
Nicholls, Stephen J; Shen, Zhongzhou; Fu, Xiaoming et al. (2005) Quantification of 3-nitrotyrosine levels using a benchtop ion trap mass spectrometry method. Methods Enzymol 396:245-66
Vasilyev, Nikolay; Williams, Timothy; Brennan, Marie-Luise et al. (2005) Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction. Circulation 112:2812-20
Menon, Sarita G; Coleman, Mitchell C; Walsh, Susan A et al. (2005) Differential susceptibility of nonmalignant human breast epithelial cells and breast cancer cells to thiol antioxidant-induced G(1)-delay. Antioxid Redox Signal 7:711-8
Morrison, Joanna P; Coleman, Mitchell C; Aunan, Elizabeth S et al. (2005) Thiol supplementation in aged animals alters antioxidant enzyme activity after heat stress. J Appl Physiol 99:2271-7

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