Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053047-03
Application #
2230790
Study Section
Special Emphasis Panel (ZHL1-CSR-S (M1))
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Arizona
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Burke, Tara K; Teng, Xinjun; Patel, Rakesh P et al. (2006) Effects of S-nitrosation on hemoglobin-induced microvascular damage. Antioxid Redox Signal 8:1093-101
Baldwin, Ann L; Demaria, Lucinda; Wiley, Elizabeth B (2005) Effects of phosphorothioate oligodeoxynucleotide on hemoglobin-induced damage to intestinal mucosa. Artif Cells Blood Substit Immobil Biotechnol 33:163-86
Baldwin, Ann L; Wiley, Elizabeth B; Alayash, Abdu I (2004) Differential effects of sodium selenite in reducing tissue damage caused by three hemoglobin-based oxygen carriers. J Appl Physiol 96:893-903
Baldwin, Ann L; Wiley, Elizabeth B; Summers, Amber G et al. (2003) Sodium selenite reduces hemoglobin-induced venular leakage in the rat mesentery. Am J Physiol Heart Circ Physiol 284:H81-91
Baldwin, Ann L; Wiley, Elizabeth B (2002) Selenium reduces hemoglobin-induced epithelial damage to intestinal mucosa. Artif Cells Blood Substit Immobil Biotechnol 30:1-22
Baldwin, Ann L; Wiley, Elizabeth B; Alayash, Abdu I (2002) Comparison of effects of two hemoglobin-based O(2) carriers on intestinal integrity and microvascular leakage. Am J Physiol Heart Circ Physiol 283:H1292-301
Wong, R K; Baldwin, A L; Heimark, R L (1999) Cadherin-5 redistribution at sites of TNF-alpha and IFN-gamma-induced permeability in mesenteric venules. Am J Physiol 276:H736-48
Baldwin, A L (1999) Modified hemoglobins produce venular interendothelial gaps and albumin leakage in the rat mesentery. Am J Physiol 277:H650-9
Wilson, L M; Baldwin, A L (1999) Environmental stress causes mast cell degranulation, endothelial and epithelial changes, and edema in the rat intestinal mucosa. Microcirculation 6:189-98
Wilson, L M; Baldwin, A L (1998) Effects of environmental stress on the architecture and permeability of the rat mesenteric microvasculature. Microcirculation 5:299-308