Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053280-02
Application #
2231117
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1995-01-15
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Melman, Lora; Geuze, Hans J; Li, Yonghe et al. (2002) Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway. Mol Biol Cell 13:3325-35
Obermoeller-McCormick, L M; Li, Y; Osaka, H et al. (2001) Dissection of receptor folding and ligand-binding property with functional minireceptors of LDL receptor-related protein. J Cell Sci 114:899-908
Liu, C X; Li, Y; Obermoeller-McCormick, L M et al. (2001) The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein. J Biol Chem 276:28889-96
Narita, M; Rudolph, A E; Miletich, J P et al. (1998) The low-density lipoprotein receptor-related protein (LRP) mediates clearance of coagulation factor Xa in vivo. Blood 91:555-60
Mast, A E; Higuchi, D A; Huang, Z F et al. (1997) Glypican-3 is a binding protein on the HepG2 cell surface for tissue factor pathway inhibitor. Biochem J 327 ( Pt 2):577-83
Warshawsky, I; Herz, J; Broze Jr, G J et al. (1996) The low density lipoprotein receptor-related protein can function independently from heparan sulfate proteoglycans in tissue factor pathway inhibitor endocytosis. J Biol Chem 271:25873-9
Warshawsky, I; Schwartz, A L (1996) The 39-kDa protein regulates LRP activity in cultured endothelial and smooth muscle cells. Eur J Cell Biol 69:156-65
Bu, G; Geuze, H J; Strous, G J et al. (1995) 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein. EMBO J 14:2269-80
Nielsen, M S; Nykjaer, A; Warshawsky, I et al. (1995) Analysis of ligand binding to the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that lipoprotein lipase and the carboxyl-terminal domain of the receptor-associated protein bind to the same site. J Biol Chem 270:23713-9
Warshawsky, I; Bu, G; Schwartz, A L (1995) Sites within the 39-kDa protein important for regulating ligand binding to the low-density lipoprotein receptor-related protein. Biochemistry 34:3404-15

Showing the most recent 10 out of 13 publications