Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053283-02
Application #
2231122
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1995-07-01
Project End
2000-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Sitrin, Robert G; Johnson, Douglas R; Pan, Pauline M et al. (2004) Lipid raft compartmentalization of urokinase receptor signaling in human neutrophils. Am J Respir Cell Mol Biol 30:233-41
Sitrin, R G; Pan, P M; Blackwood, R A et al. (2001) Cutting edge: evidence for a signaling partnership between urokinase receptors (CD87) and L-selectin (CD62L) in human polymorphonuclear neutrophils. J Immunol 166:4822-5
Sitrin, R G; Pan, P M; Harper, H A et al. (2000) Clustering of urokinase receptors (uPAR; CD87) induces proinflammatory signaling in human polymorphonuclear neutrophils. J Immunol 165:3341-9
Sitrin, R G; Pan, P M; Harper, H A et al. (1999) Urokinase receptor (CD87) aggregation triggers phosphoinositide hydrolysis and intracellular calcium mobilization in mononuclear phagocytes. J Immunol 163:6193-200
Sitrin, R G; Pan, P M; Srikanth, S et al. (1998) Fibrinogen activates NF-kappa B transcription factors in mononuclear phagocytes. J Immunol 161:1462-70
Sitrin, R G; Todd 3rd, R F; Albrecht, E et al. (1996) The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes. J Clin Invest 97:1942-51