Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053318-02
Application #
2231174
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1995-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Physiology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Koval, Michael; Billaud, Marie; Straub, Adam C et al. (2011) Spontaneous lung dysfunction and fibrosis in mice lacking connexin 40 and endothelial cell connexin 43. Am J Pathol 178:2536-46
Figueroa, Xavier F; Duling, Brian R (2009) Gap junctions in the control of vascular function. Antioxid Redox Signal 11:251-66
Veliz, Loreto P; Gonzalez, Francisco G; Duling, Brian R et al. (2008) Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo. Am J Physiol Heart Circ Physiol 295:H1056-H1066
Figueroa, Xavier F; Duling, Brian R (2008) Dissection of two Cx37-independent conducted vasodilator mechanisms by deletion of Cx40: electrotonic versus regenerative conduction. Am J Physiol Heart Circ Physiol 295:H2001-7
Isakson, Brant E; Best, Angela K; Duling, Brian R (2008) Incidence of protein on actin bridges between endothelium and smooth muscle in arterioles demonstrates heterogeneous connexin expression and phosphorylation. Am J Physiol Heart Circ Physiol 294:H2898-904
Isakson, Brant E; Ramos, Susan I; Duling, Brian R (2007) Ca2+ and inositol 1,4,5-trisphosphate-mediated signaling across the myoendothelial junction. Circ Res 100:246-54
Figueroa, Xavier F; Chen, Chien-Chang; Campbell, Kevin P et al. (2007) Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone? Am J Physiol Heart Circ Physiol 293:H1371-83
Liao, Yongbo; Regan, Christopher P; Manabe, Ichiro et al. (2007) Smooth muscle-targeted knockout of connexin43 enhances neointimal formation in response to vascular injury. Arterioscler Thromb Vasc Biol 27:1037-42
Isakson, Brant E; Damon, David N; Day, Kathleen H et al. (2006) Connexin40 and connexin43 in mouse aortic endothelium: evidence for coordinated regulation. Am J Physiol Heart Circ Physiol 290:H1199-205
Isakson, Brant E; Duling, Brian R (2005) Heterocellular contact at the myoendothelial junction influences gap junction organization. Circ Res 97:44-51

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