Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL054145-05A1
Application #
6287721
Study Section
Surgery and Bioengineering Study Section (SB)
Program Officer
Wassef, Momtaz K
Project Start
1996-08-01
Project End
2005-05-31
Budget Start
2001-06-01
Budget End
2002-05-31
Support Year
5
Fiscal Year
2001
Total Cost
$343,047
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Osborn, Eric A; Rabodzey, Aleksandr; Dewey Jr, C Forbes et al. (2006) Endothelial actin cytoskeleton remodeling during mechanostimulation with fluid shear stress. Am J Physiol Cell Physiol 290:C444-52
Dewey Jr, C Forbes (2002) Haemodynamic flow: symmetry and synthesis. Biorheology 39:541-9
Nakamura, Fumihiko; Osborn, Eric; Janmey, Paul A et al. (2002) Comparison of filamin A-induced cross-linking and Arp2/3 complex-mediated branching on the mechanics of actin filaments. J Biol Chem 277:9148-54
McGrath, J L; Osborn, E A; Tardy, Y S et al. (2000) Regulation of the actin cycle in vivo by actin filament severing. Proc Natl Acad Sci U S A 97:6532-7
Cheng, Y; Hartemink, C A; Hartwig, J H et al. (2000) Three-dimensional reconstruction of the actin cytoskeleton from stereo images. J Biomech 33:105-13
Hartwig, J H; Barkalow, K; Azim, A et al. (1999) The elegant platelet: signals controlling actin assembly. Thromb Haemost 82:392-8
Ohta, Y; Suzuki, N; Nakamura, S et al. (1999) The small GTPase RalA targets filamin to induce filopodia. Proc Natl Acad Sci U S A 96:2122-8
McGrath, J L; Hartwig, J H; Tardy, Y et al. (1998) Measuring actin dynamics in endothelial cells. Microsc Res Tech 43:385-94
McGrath, J L; Tardy, Y; Dewey Jr, C F et al. (1998) Simultaneous measurements of actin filament turnover, filament fraction, and monomer diffusion in endothelial cells. Biophys J 75:2070-8
Satcher, R; Dewey Jr, C F; Hartwig, J H (1997) Mechanical remodeling of the endothelial surface and actin cytoskeleton induced by fluid flow. Microcirculation 4:439-53