Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL054749-08
Application #
6794020
Study Section
Hematology Subcommittee 2 (HEM)
Program Officer
Ganguly, Pankaj
Project Start
1995-09-01
Project End
2005-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
8
Fiscal Year
2004
Total Cost
$256,620
Indirect Cost

  Institution

Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Rauova, Lubica; Zhai, Li; Kowalska, M Anna et al. (2006) Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications. Blood 107:2346-53
Suvarna, Shayela; Rauova, Lubica; McCracken, Emily K E et al. (2005) PF4/heparin complexes are T cell-dependent antigens. Blood 106:929-31
McKenzie, Steven E; Reilly, Michael P (2004) Heparin-induced thrombocytopenia and other immune thrombocytopenias: lessons from mouse models. Semin Thromb Hemost 30:559-68
Eslin, Don E; Zhang, Chunyan; Samuels, Kathleen J et al. (2004) Transgenic mice studies demonstrate a role for platelet factor 4 in thrombosis: dissociation between anticoagulant and antithrombotic effect of heparin. Blood 104:3173-80
Kufrin, Dubravka; Eslin, Don E; Bdeir, Khalil et al. (2003) Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets. Blood 102:926-33
Li, Zhong Q; Liu, Weiyi; Park, Kwang S et al. (2002) Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody. Blood 99:1230-6
Konkle, B A; Bauer, T L; Arepally, G et al. (2001) Heparin-induced thrombocytopenia: bovine versus porcine heparin in cardiopulmonary bypass surgery. Ann Thorac Surg 71:1920-4
Arepally, G M; Kamei, S; Park, K S et al. (2000) Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies. Blood 95:1533-40
Kowalska, M A; Ratajczak, J; Hoxie, J et al. (1999) Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: determination of response to stromal-derived factor-1 by megakaryocytes and platelets. Br J Haematol 104:220-9
Aceto, J; Kieber-Emmons, T; Cines, D B (1999) Carboxy-terminal processing of the urokinase receptor: implications for substrate recognition and glycosylphosphatidylinositol anchor addition. Biochemistry 38:992-1001

Showing the most recent 10 out of 16 publications