Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL055487-03
Application #
2688209
Study Section
Metabolism Study Section (MET)
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1997-09-01
Budget End
1998-07-31
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
King, Victoria L; Cassis, Lisa A; Daugherty, Alan (2007) Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice. Am J Pathol 171:2040-7
Whitman, Stewart C; Kurowska, Elzbieta M; Manthey, John A et al. (2005) Nobiletin, a citrus flavonoid isolated from tangerines, selectively inhibits class A scavenger receptor-mediated metabolism of acetylated LDL by mouse macrophages. Atherosclerosis 178:25-32
Urbas, Aaron; Manning, Michael W; Daugherty, Alan et al. (2003) Near-infrared spectrometry of abdominal aortic aneurysm in the ApoE-/- mouse. Anal Chem 75:3650-5
Daugherty, Alan; Whitman, Stewart C (2003) Quantification of atherosclerosis in mice. Methods Mol Biol 209:293-309
Kosswig, Ninetta; Rice, Stuart; Daugherty, Alan et al. (2003) Class A scavenger receptor-mediated adhesion and internalization require distinct cytoplasmic domains. J Biol Chem 278:34219-25
Whitman, Stewart C; Rateri, Debra L; Szilvassy, Stephen J et al. (2002) Macrophage-specific expression of class A scavenger receptors in LDL receptor(-/-) mice decreases atherosclerosis and changes spleen morphology. J Lipid Res 43:1201-8
King, Victoria L; Szilvassy, Stephen J; Daugherty, Alan (2002) Interleukin-4 deficiency promotes gallstone formation. J Lipid Res 43:768-71
King, Victoria L; Szilvassy, Stephen J; Daugherty, Alan (2002) Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice. Arterioscler Thromb Vasc Biol 22:456-61
Webb, Nancy R; de Beer, Maria C; Yu, Jin et al. (2002) Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice. J Lipid Res 43:1421-8
Daugherty, A; Kosswig, N; Cornicelli, J A et al. (2001) Macrophage-specific expression of class A scavenger receptors enhances granuloma formation in the absence of increased lipid deposition. J Lipid Res 42:1049-55

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