The major aim is to develop and test various educational strategies targeting TB-infected adolescents at two health centers in Los Angeles in an experimental design to assess the relative effectiveness on medication adherence, appointment keeping, and completion of therapy. The educational content and modalities are based on an intervention-oriented model of behavioral action derived from the theory of reasoned action, the theory of planned behavior, and the transtheoretical model. An experimental four group design will be used to assess the independent and combined effects of peer counseling, a participant/parent contingency contract intervention, and a combination of peer counseling and contingency contracting, compared with a usual care control group. A total of 880 participants will be randomly assigned to one of the four groups. In addition to assessing the impact of the intervention, analyses will compare the relative importance of the hypothesized influencing and mediating factors on behavior. Cost-effectiveness analyses will also be conducted. During the later stages of the study, clinic staff from throughout Los Angeles County will be trained and encouraged to integrate the strategies that appear to be effective into their clinic setting.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL055770-03
Application #
2519556
Study Section
Special Emphasis Panel (ZHL1-CSR-I (S1))
Project Start
1995-09-30
Project End
2000-08-31
Budget Start
1997-09-01
Budget End
1998-08-31
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Coly, A; Morisky, D (2004) Predicting completion of treatment among foreign-born adolescents treated for latent tuberculosis infection in Los Angeles. Int J Tuberc Lung Dis 8:703-10
Sneed, Carl D; Morisky, Donald E; Rotheram-Borus, Mary Jane et al. (2004) Indices of lifetime polydrug use among adolescents. J Adolesc 27:239-49
Morisky, Donald E; Ebin, Vicki J; Malotte, C Kevin et al. (2003) Assessment of tuberculosis treatment completion in an ethnically diverse population using two data sources. Implications for treatment interventions. Eval Health Prof 26:43-58
Cabrera, D M; Morisky, D E; Chin, S (2002) Development of a tuberculosis education booklet for Latino immigrant patients. Patient Educ Couns 46:117-24
Sneed, C D; Morisky, D E; Rotheram-Borus, M J et al. (2001) 'Don't know' and 'didn't think of it': condom use at first intercourse by Latino adolescents. AIDS Care 13:303-8
Ebin, V J; Sneed, C D; Morisky, D E et al. (2001) Acculturation and interrelationships between problem and health-promoting behaviors among Latino adolescents. J Adolesc Health 28:62-72
Sneed, C D; Morisky, D E; Rotheram-Borus, M J et al. (2001) Patterns of adolescent alcohol, cigarette, and marijuana use over a 6-month period. Addict Behav 26:415-23
Salabarria-Pena, Y; Trout, P T; Gill, J K et al. (2001) Effects of acculturation and psychosocial factors in Latino adolescents' TB-related behaviors. Ethn Dis 11:661-75