Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL055969-04
Application #
2677068
Study Section
AIDS and Related Research Study Section 5 (ARRE)
Project Start
1995-09-30
Project End
2000-08-31
Budget Start
1997-11-01
Budget End
1998-08-31
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Guidry, Tera V; Olsen, Margaret; Kil, Ki-Soo et al. (2004) Failure of CD1D-/- mice to elicit hypersensitive granulomas to mycobacterial cord factor trehalose 6,6'-dimycolate. J Interferon Cytokine Res 24:362-71
Actor, Jeffrey K; Indrigo, Jessica; Beachdel, Christopher M et al. (2002) Mycobacterial glycolipid cord factor trehalose 6,6'-dimycolate causes a decrease in serum cortisol during the granulomatous response. Neuroimmunomodulation 10:270-82
Actor, J K; Olsen, M; Hunter Jr, R L et al. (2001) Dysregulated response to mycobacterial cord factor trehalose-6,6'-dimycolate in CD1D-/- mice. J Interferon Cytokine Res 21:1089-96
Actor, J K; Breij, E; Wetsel, R A et al. (2001) A role for complement C5 in organism containment and granulomatous response during murine tuberculosis. Scand J Immunol 53:464-74
Watson, V E; Hill, L L; Owen-Schaub, L B et al. (2000) Apoptosis in mycobacterium tuberculosis infection in mice exhibiting varied immunopathology. J Pathol 190:211-20
Perez, R L; Roman, J; Roser, S et al. (2000) Cytokine message and protein expression during lung granuloma formation and resolution induced by the mycobacterial cord factor trehalose-6,6'-dimycolate. J Interferon Cytokine Res 20:795-804
Jagannath, C; Hoffmann, H; Sepulveda, E et al. (2000) Hypersusceptibility of A/J mice to tuberculosis is in part due to a deficiency of the fifth complement component (C5). Scand J Immunol 52:369-79
Jagannath, C; Sepulveda, E; Actor, J K et al. (2000) Effect of poloxamer CRL-1072 on drug uptake and nitric-oxide-mediated killing of Mycobacterium avium by macrophages. Immunopharmacology 48:185-97
Actor, J K; Leonard, C D; Watson, V E et al. (2000) Cytokine mRNA expression and serum cortisol evaluation during murine lung inflammation induced by Mycobacterium tuberculosis. Comb Chem High Throughput Screen 3:343-51
Jagannath, C; Emanuele, M R; Hunter, R L (1999) Activities of poloxamer CRL-1072 against Mycobacterium avium in macrophage culture and in mice. Antimicrob Agents Chemother 43:2898-903

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