Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL056620-01
Application #
2235113
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Sanbe, Atsushi; Gulick, James; Hanks, Mark C et al. (2003) Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter. Circ Res 92:609-16
Wang, X; Osinska, H; Klevitsky, R et al. (2001) Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice. Circ Res 89:84-91
Schwartzbauer, G; Robbins, J (2001) The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival. J Biol Chem 276:35786-93
Yang, Q; Osinska, H; Klevitsky, R et al. (2001) Phenotypic deficits in mice expressing a myosin binding protein C lacking the titin and myosin binding domains. J Mol Cell Cardiol 33:1649-58
Sanbe, A; Gulick, J; Fewell, J et al. (2001) Examining the in vivo role of the amino terminus of the essential myosin light chain. J Biol Chem 276:32682-6
Wang, X; Osinska, H; Dorn 2nd, G W et al. (2001) Mouse model of desmin-related cardiomyopathy. Circulation 103:2402-7
Yang, Q; Hewett, T E; Klevitsky, R et al. (2001) PKA-dependent phosphorylation of cardiac myosin binding protein C in transgenic mice. Cardiovasc Res 51:80-8
Sanbe, A; Nelson, D; Gulick, J et al. (2000) In vivo analysis of an essential myosin light chain mutation linked to familial hypertrophic cardiomyopathy. Circ Res 87:296-302
James, J; Zhang, Y; Osinska, H et al. (2000) Transgenic modeling of a cardiac troponin I mutation linked to familial hypertrophic cardiomyopathy. Circ Res 87:805-11
James, J; Sanbe, A; Yager, K et al. (2000) Genetic manipulation of the rabbit heart via transgenesis. Circulation 101:1715-21

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