Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL056668-01
Application #
2235151
Study Section
Metabolism Study Section (MET)
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Lau, Paul P; Li, Lan; Merched, Aksam J et al. (2006) Nicotine induces proinflammatory responses in macrophages and the aorta leading to acceleration of atherosclerosis in low-density lipoprotein receptor(-/-) mice. Arterioscler Thromb Vasc Biol 26:143-9
el Marjou, Fatima; Janssen, Klaus-Peter; Chang, Benny Hung-Junn et al. (2004) Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis 39:186-93
Lau, Paul P; Chan, Lawrence (2003) Involvement of a chaperone regulator, Bcl2-associated athanogene-4, in apolipoprotein B mRNA editing. J Biol Chem 278:52988-96
Liao, Wei; Chang, Benny Hung-Junn; Mancini, Michael et al. (2003) Ubiquitin-dependent and -independent proteasomal degradation of apoB associated with endoplasmic reticulum and Golgi apparatus, respectively, in HepG2 cells. J Cell Biochem 89:1019-29
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Lau, P P; Villanueva, H; Kobayashi, K et al. (2001) A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing. J Biol Chem 276:46445-52
Lau, P P; Chang, B H; Chan, L (2001) Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome. Biochem Biophys Res Commun 282:977-83
Liao, W; Chan, L (2000) Apolipoprotein B, a paradigm for proteins regulated by intracellular degradation, does not undergo intracellular degradation in CaCo2 cells. J Biol Chem 275:3950-6
Chan, L; Chang, B H; Liao, W et al. (2000) Apolipoprotein B: from editosome to proteasome. Recent Prog Horm Res 55:93-125; discussion 126
Teng, B B; Ochsner, S; Zhang, Q et al. (1999) Mutational analysis of apolipoprotein B mRNA editing enzyme (APOBEC1). structure-function relationships of RNA editing and dimerization. J Lipid Res 40:623-35

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