Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL056778-01
Application #
2235237
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Araten, David J; Luzzatto, Lucio (2006) The mutation rate in PIG-A is normal in patients with paroxysmal nocturnal hemoglobinuria (PNH). Blood 108:734-6
Ellis, Nathan A; Kirchhoff, Tomas; Mitra, Nandita et al. (2006) Localization of breast cancer susceptibility loci by genome-wide SNP linkage disequilibrium mapping. Genet Epidemiol 30:48-61
Araten, David J; Thaler, Howard T; Luzzatto, Lucio (2005) High incidence of thrombosis in African-American and Latin-American patients with Paroxysmal Nocturnal Haemoglobinuria. Thromb Haemost 93:88-91
Araten, David J; Golde, David W; Zhang, Rong H et al. (2005) A quantitative measurement of the human somatic mutation rate. Cancer Res 65:8111-7
Mitra, Nandita; Ye, Tian-Zhang; Smith, Alex et al. (2004) Localization of cancer susceptibility genes by genome-wide single-nucleotide polymorphism linkage-disequilibrium mapping. Cancer Res 64:8116-25
Karadimitris, Anastasios; Araten, David J; Luzzatto, Lucio et al. (2003) Severe telomere shortening in patients with paroxysmal nocturnal hemoglobinuria affects both GPI- and GPI+ hematopoiesis. Blood 102:514-6
Bessler, Monica; Rosti, Vittorio; Peng, Yufeng et al. (2002) Glycosylphosphatidylinositol-linked proteins are required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. Eur J Immunol 32:2607-16
Araten, D J; Bessler, M; McKenzie, S et al. (2002) Dynamics of hematopoiesis in paroxysmal nocturnal hemoglobinuria (PNH): no evidence for intrinsic growth advantage of PNH clones. Leukemia 16:2243-8
Karadimitris, A; Li, K; Notaro, R et al. (2001) Association of clonal T-cell large granular lymphocyte disease and paroxysmal nocturnal haemoglobinuria (PNH): further evidence for a pathogenetic link between T cells, aplastic anaemia and PNH. Br J Haematol 115:1010-4
Araten, D J; Swirsky, D; Karadimitris, A et al. (2001) Cytogenetic and morphological abnormalities in paroxysmal nocturnal haemoglobinuria. Br J Haematol 115:360-8

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