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Sahu, Ranjit K; Nacharaju, Parimala; Manjula, Belur N et al. (2009) Induced plasma expander-like properties as a function of PEG-chains on extension arm facilitated PEGylation of albumin: ""mushroom to brush-like"" conformational transition of the PEG-albumin conjugate. Artif Cells Blood Substit Immobil Biotechnol 37:245-56
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Hu, Tao; Li, Dongxia; Manjula, Belur N et al. (2009) PEGylation of Val-1(alpha) destabilizes the tetrameric structure of hemoglobin. Biochemistry 48:608-16
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Li, Dongxia; Hu, Tao; Manjula, Belur N et al. (2009) Extension arm facilitated pegylation of alphaalpha-hemoglobin with modifications targeted exclusively to amino groups: functional and structural advantages of free Cys-93(beta) in the PEG-Hb adduct. Bioconjug Chem 20:2062-70
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Meng, Fantao; Manjula, Belur N; Tsai, Amy G et al. (2009) Hexa-thiocarbamoyl phenyl PEG5K Hb: vasoactivity and structure: influence of rigidity of the conjugation linkage on the PEGylation induced plasma expander-like solution properties of PEG-Hb adducts. Protein J 28:199-212
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Hu, Tao; Li, Dongxia; Manjula, Belur N et al. (2008) Autoxidation of the site-specifically PEGylated hemoglobins: role of the PEG chains and the sites of PEGylation in the autoxidation. Biochemistry 47:10981-90
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Meng, Fantao; Manjula, Belur N; Smith, Paul K et al. (2008) PEGylation of human serum albumin: reaction of PEG-phenyl-isothiocyanate with protein. Bioconjug Chem 19:1352-60
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Ananda, K; Nacharaju, Parimala; Smith, Paul K et al. (2008) Analysis of functionalization of methoxy-PEG as maleimide-PEG. Anal Biochem 374:231-42
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Li, Dongxia; Manjula, Belur N; Ho, Nancy T et al. (2007) Molecular aspects of the high oxygen affinity of non-hypertensive hexa pegylated hemoglobin, [(SP-PEG5K)(6)-Hb]. Artif Cells Blood Substit Immobil Biotechnol 35:19-29
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Nacharaju, Parimala; Manjula, Belur N; Acharya, Seetharama A (2007) Thiolation mediated pegylation platform to generate functional universal red blood cells. Artif Cells Blood Substit Immobil Biotechnol 35:107-18
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Hu, Tao; Manjula, Belur N; Li, Dongxia et al. (2007) Influence of intramolecular cross-links on the molecular, structural and functional properties of PEGylated haemoglobin. Biochem J 402:143-51
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